Abstract：
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity defects, Rh or ABO incompatibility, non-immune hydrops fetalis, infections, congenital cardiac anomalies, metabolic diseases and hematologic diseases such as α-thalassemia. This review provides an overview of syndromic and single gene disorders associated with fetal pleural effusion that is useful for genetic counseling and fetal therapy at prenatal diagnosis of fetal pleural effusion.
摘要：
据报道，胎儿胸腔积液与染色体异常有关，遗传综合征，阻塞性尿路病,淋巴管异常如努南综合征，放射病和先天性淋巴异常，胸腔缺损，Rh或ABO不兼容，非免疫性胎儿水肿,感染,先天性心脏异常,代谢性疾病和血液病，如α-地中海贫血。这篇综述概述了与胎儿胸腔积液相关的综合征和单基因疾病，可用于胎儿胸腔积液的产前诊断中的遗传咨询和胎儿治疗。
