Abstract：
BACKGROUND: Coronavirus disease 2019 (COVID-19) can have symptoms like many neurological diseases, and one of the rare forms of these presentations is opsoclonus-myoclonus ataxia syndrome (OMAS). The pathogenesis of OMAS in adults has not been clearly elucidated and OMAS can be fatal.
METHODS: We present a 71-year-old male patient who was admitted to the emergency department with complaints of involuntary tremor-like movements in his hands, feet and mouth, and speech impediment for three days, and was followed up with COVID-19. The patient was diagnosed with OMAS and clonazepam treatment was started. He died three days later due to respiratory arrest. Our case is the first case diagnosed with COVID-19-associated OMAS in Turkey.
CONCLUSIONS: OMAS has no definitive treatment. Early diagnosis and initiation of corticosteroids and intravenous immunoglobulin (IVIG) therapy, if necessary, can be life-saving. In COVID-19 patients with unexplained clinical findings, awareness of different and rare diseases and a multidisciplinary approach has vital importance.
METHODS: We present a 71-year-old male patient who was admitted to the emergency department with complaints of involuntary tremor-like movements in his hands, feet and mouth, and speech impediment for three days, and was followed up with COVID-19. The patient was diagnosed with OMAS and clonazepam treatment was started. He died three days later due to respiratory arrest. Our case is the first case diagnosed with COVID-19-associated OMAS in Turkey.
CONCLUSIONS: OMAS has no definitive treatment. Early diagnosis and initiation of corticosteroids and intravenous immunoglobulin (IVIG) therapy, if necessary, can be life-saving. In COVID-19 patients with unexplained clinical findings, awareness of different and rare diseases and a multidisciplinary approach has vital importance.
摘要：
背景：2019年冠状病毒病（COVID-19）可能有许多神经系统疾病的症状，这些表现的罕见形式之一是眼阵挛性-肌阵挛性共济失调综合征（OMAS）。成人OMAS的发病机制尚未明确阐明，OMAS可能是致命的。
方法：我们介绍了一名71岁的男性患者，他因手部不自主的震颤样运动而入院，脚和嘴,三天的言语障碍，并随访COVID-19。患者被诊断为OMAS，并开始氯硝西泮治疗。三天后，他因呼吸骤停而死亡。我们的病例是土耳其首例诊断为COVID-19相关OMAS的病例。
结论：OMAS没有明确的治疗方法。早期诊断和开始糖皮质激素和静脉注射免疫球蛋白（IVIG）治疗，如有必要,可以挽救生命。在具有无法解释的临床表现的COVID-19患者中，对不同和罕见疾病的认识和多学科方法至关重要。
方法：我们介绍了一名71岁的男性患者，他因手部不自主的震颤样运动而入院，脚和嘴,三天的言语障碍，并随访COVID-19。患者被诊断为OMAS，并开始氯硝西泮治疗。三天后，他因呼吸骤停而死亡。我们的病例是土耳其首例诊断为COVID-19相关OMAS的病例。
结论：OMAS没有明确的治疗方法。早期诊断和开始糖皮质激素和静脉注射免疫球蛋白（IVIG）治疗，如有必要,可以挽救生命。在具有无法解释的临床表现的COVID-19患者中，对不同和罕见疾病的认识和多学科方法至关重要。
