PDF(Pubmed)
Abstract：
Neutropenic enterocolitis (NEC), also referred to as typhlitis, is a condition associated with a high mortality risk and primarily manifests in immunocompromised patients. It is characterized by ulceration, edema, and hemorrhage affecting the bowel wall. The underlying cause of NEC is postulated as an immunocompromised condition that facilitates bacterial infiltration through compromised bowel mucosa. The high mortality rate is attributable to bowel necrosis, culminating in perforation and sepsis. This report describes a case involving a patient with metastatic seminoma who exhibited seizure-like activity, fever, Streptococcus gallolyticus bacteremia, and NEC. The patient underwent treatment involving broad-spectrum antibiotics and filgrastim. The patient\'s neutropenia resolved leading to discharge on oral antibiotics. The case reported is unique, as it links NEC to Streptococcus gallolyticus and seminoma. Streptococcus gallolyticus has not been previously associated with NEC.
摘要：
中性粒细胞减少性小肠结肠炎(NEC),也被称为伤寒，是一种与高死亡率风险相关的疾病，主要表现在免疫功能低下的患者中。它的特点是溃疡，水肿,出血影响肠壁.NEC的根本原因被假定为促进细菌通过受损肠粘膜浸润的免疫受损病症。高死亡率归因于肠坏死，最终导致穿孔和败血症。该报告描述了一例涉及转移性精原细胞瘤的患者，该患者表现出癫痫样活动，发烧,溶胆链球菌菌血症,和NEC。患者接受了包括广谱抗生素和非格司亭的治疗。患者的中性粒细胞减少症消退，导致口服抗生素出院。报告的病例是独特的，因为它将NEC与溶胆链球菌和精原细胞瘤联系起来。溶胆链球菌以前与NEC无关。
