PDF(Pubmed)
Abstract：
UNASSIGNED: The objective of this study is to investigate the incidence and risk factors for stone formation and recurrence in patients with neurogenic lower urinary tract dysfunction (NLUTD) in a real-world cohort.
UNASSIGNED: A retrospective cohort study was conducted on all patients with NLUTD who underwent bladder stone treatment between 2010 and 2022. Univariate and multivariate Cox models were used to identify the potential risk factors for stone recurrence.
UNASSIGNED: Among 114 patients included in the study, 30% experienced stone recurrence. The most common stone components were carbonate apatite phosphate and magnesium ammonium phosphate. The overall recurrence rate was 14 cases per 100 patient years. Neurogenic detrusor overactivity had the highest recurrence rate. Risk factors for stone recurrence in the multivariate analysis were intermittent and suprapubic catheterization, and recurrent urinary tract infection (rUTI).
UNASSIGNED: Patients experienced multiple bladder stone recurrences. Close monitoring of bladder pressure and UTI with restrictive catheter application may reduce the risk of stone recurrence.
UNASSIGNED: A retrospective cohort study was conducted on all patients with NLUTD who underwent bladder stone treatment between 2010 and 2022. Univariate and multivariate Cox models were used to identify the potential risk factors for stone recurrence.
UNASSIGNED: Among 114 patients included in the study, 30% experienced stone recurrence. The most common stone components were carbonate apatite phosphate and magnesium ammonium phosphate. The overall recurrence rate was 14 cases per 100 patient years. Neurogenic detrusor overactivity had the highest recurrence rate. Risk factors for stone recurrence in the multivariate analysis were intermittent and suprapubic catheterization, and recurrent urinary tract infection (rUTI).
UNASSIGNED: Patients experienced multiple bladder stone recurrences. Close monitoring of bladder pressure and UTI with restrictive catheter application may reduce the risk of stone recurrence.
摘要：
■这项研究的目的是调查真实世界队列中神经源性下尿路功能障碍（NLUTD）患者结石形成和复发的发生率和危险因素。
■对2010年至2022年接受膀胱结石治疗的所有NULTD患者进行了回顾性队列研究。使用单变量和多变量Cox模型来确定结石复发的潜在危险因素。
■在纳入研究的114名患者中，30%经历结石复发。最常见的石头成分是碳酸盐磷灰石磷酸盐和磷酸镁铵。总复发率为每100例患者年14例。神经源性逼尿肌过度活动的复发率最高。多变量分析中结石复发的危险因素是间歇性和耻骨上导管插入术，和复发性尿路感染（rUTI）。
■患者出现多次膀胱结石复发。通过限制性导管应用密切监测膀胱压力和UTI可以降低结石复发的风险。
■对2010年至2022年接受膀胱结石治疗的所有NULTD患者进行了回顾性队列研究。使用单变量和多变量Cox模型来确定结石复发的潜在危险因素。
■在纳入研究的114名患者中，30%经历结石复发。最常见的石头成分是碳酸盐磷灰石磷酸盐和磷酸镁铵。总复发率为每100例患者年14例。神经源性逼尿肌过度活动的复发率最高。多变量分析中结石复发的危险因素是间歇性和耻骨上导管插入术，和复发性尿路感染（rUTI）。
■患者出现多次膀胱结石复发。通过限制性导管应用密切监测膀胱压力和UTI可以降低结石复发的风险。
