PDF(Pubmed)
Abstract：
Breast cancer accounts for one in three new cancer cases in women each year. Despite having a higher survival rate than other cancers, it is associated with various side effects, including anorgasmia, vaginismus, hair loss, and decreased libido. This review aims to explore trends in the incidence of sexual dysfunction in breast cancer survivors, the etiology of sexual dysfunction, and the role of factors such as family history, age, duration of marriage, and depression in predisposing patients. We summarize the limitations of the treatment modalities already used to cater to sexual dysfunction in breast cancer survivors and patients. The authors conducted searches on databases such as PubMed and Google Scholar using relevant search terms: sexual dysfunction, breast cancer, breast cancer survivors, chemotherapy, dyspareunia, vaginismus, and anorgasmia from 1997-2023. The inclusion criteria encompassed all types of articles with abstracts or titles indicating research on sexual dysfunction in breast cancer survivors in Asia. A total of 64 articles were included out of which 10 were systematic reviews and meta-analyses. The literature search yielded results showing high incidence rates of breast cancer in Asia (45.4%), with 31.6%-91.2% of breast cancer survivors likely to experience sexual dysfunction. Regional differences were noted, as female sexual dysfunction occurred in 74.1% of Asian breast cancer women. Further randomized controlled trials should be conducted to assess the effectiveness of treatment modalities. Personalized approaches should be tailored to address beliefs, such as the potential impact of sexual activity on disease recovery. Utilizing a family history of breast cancer as a preemptive tool can help reduce the risk of developing female sexual dysfunction in survivors, and factors such as age and depression should be considered when formulating solutions.
摘要：
乳腺癌占每年女性新发癌症病例的三分之一。尽管有比其他癌症更高的存活率，它与各种副作用有关，包括性高潮,阴道痉挛,脱发,性欲下降。本文旨在探讨乳腺癌幸存者性功能障碍的发生率趋势。性功能障碍的病因，以及家族史等因素的作用，年龄,婚姻的持续时间,和易感患者的抑郁。我们总结了已经用于治疗乳腺癌幸存者和患者性功能障碍的治疗方式的局限性。作者使用相关搜索词在PubMed和GoogleScholar等数据库上进行了搜索：性功能障碍，乳腺癌,乳腺癌幸存者,化疗,性交困难,阴道痉挛,和1997-2023年的性高潮。入选标准包括所有类型的文章，其摘要或标题表明亚洲乳腺癌幸存者性功能障碍的研究。共纳入64篇文章，其中10篇为系统评价和荟萃分析。文献检索结果显示亚洲乳腺癌发病率高(45.4%),31.6％-91.2％的乳腺癌幸存者可能会出现性功能障碍。注意到区域差异，由于女性性功能障碍发生在74.1%的亚洲乳腺癌女性中。应进行进一步的随机对照试验以评估治疗方式的有效性。个性化的方法应该是针对信仰而定制的，例如性活动对疾病康复的潜在影响。利用乳腺癌家族史作为先发制人的工具可以帮助降低幸存者发生女性性功能障碍的风险，制定解决方案时应考虑年龄和抑郁等因素。
