关键词: Prototheca antifungals epidemiology protothecosis

Mesh : Humans Antifungal Agents / therapeutic use China / epidemiology Fluconazole / therapeutic use administration & dosage Prototheca / isolation & purification Skin Diseases, Infectious / drug therapy microbiology epidemiology diagnosis

来  源:   DOI:10.1111/jocd.16272

Abstract:
BACKGROUND: Protothecosis is an infection of humans and animals caused by a rare conditionally pathogenic fungus (prototheca). It can occur in immunocompromised or normal patients.
OBJECTIVE: To describe the epidemiology of prototheca infection in China.
METHODS: We report a case of successful treatment of cutaneous protothecosis with fluconazole and analyzed the epidemiological characteristics, risk factors, clinical manifestations, diagnosis, treatment and prognosis of prototheca infections in China.
RESULTS: We describe this case and 29 cases of prototheca infections in China. At present, Prototheca wickerhamii (Pw) infection is the most common infection in China, and single or combined itraconazole is the preferred treatment.
CONCLUSIONS: These results provide detailed information and relevant clinical treatment strategies for the diagnosis and treatment of protothecosis in China.
摘要:
背景:原虫病是由一种罕见的条件致病性真菌(原虫)引起的人类和动物感染。它可以发生在免疫受损或正常患者中。
目的:描述中国原虫感染的流行病学。
方法:报告1例成功应用氟康唑治疗皮肤原虫病的病例,并分析其流行病学特征,危险因素,临床表现,诊断,中国原虫感染的治疗和预后。
结果:我们描述了该病例和中国的29例原叶藻感染病例。目前,假单胞菌感染是我国最常见的感染,单一或联合伊曲康唑是首选治疗方法。
结论:这些结果为中国原虫病的诊断和治疗提供了详细信息和相关的临床治疗策略。
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