PDF(Pubmed)
Abstract：
UNASSIGNED: Hepatic angiomyolipoma (HAML) is a rare liver tumor composed of blood vessels, smooth muscle, and fat cells. HAML occurs across a wide age range, with symptoms including abdominal discomfort, bloating, and weight loss. Diagnosis is challenging due to varied imaging appearances, but histopathological examination supplemented by immunohistochemical analysis, particularly using HMB-45, is definitive.
METHODS: A 33-year-old man presented with a two-year history of right upper quadrant abdominal pain, occasionally relieved with analgesics but worsening over the past month and a half. Examinations revealed a soft, non-distended abdomen with a palpable liver. Laboratory tests, including viral markers and tumor markers were normal. Contrast-enhanced CT revealed a well-defined oval mass in liver segment III with heterogeneous enhancement leading to provisional diagnosis of HAML. The patient underwent a successful en bloc excision with no intraoperative or postoperative complications.
UNASSIGNED: Surgical resection is recommended for symptomatic cases or inconclusive biopsies, with stringent follow-up necessary due to the potential for recurrence and association with other malignancies.
CONCLUSIONS: HAML may present with prolonged nonspecific abdominal symptoms. CT imaging aids in diagnosing cases with abundant fatty tissue. En bloc tumor excision proves safe and effective in treating symptomatic presentations.
METHODS: A 33-year-old man presented with a two-year history of right upper quadrant abdominal pain, occasionally relieved with analgesics but worsening over the past month and a half. Examinations revealed a soft, non-distended abdomen with a palpable liver. Laboratory tests, including viral markers and tumor markers were normal. Contrast-enhanced CT revealed a well-defined oval mass in liver segment III with heterogeneous enhancement leading to provisional diagnosis of HAML. The patient underwent a successful en bloc excision with no intraoperative or postoperative complications.
UNASSIGNED: Surgical resection is recommended for symptomatic cases or inconclusive biopsies, with stringent follow-up necessary due to the potential for recurrence and association with other malignancies.
CONCLUSIONS: HAML may present with prolonged nonspecific abdominal symptoms. CT imaging aids in diagnosing cases with abundant fatty tissue. En bloc tumor excision proves safe and effective in treating symptomatic presentations.
摘要：
■肝血管平滑肌脂肪瘤（HAML）是一种罕见的由血管组成的肝脏肿瘤，平滑肌,和脂肪细胞。HAML发生在广泛的年龄范围内，症状包括腹部不适，腹胀,和减肥。由于影像表现各异,诊断具有挑战性。但组织病理学检查辅以免疫组织化学分析，特别是使用HMB-45，是确定的。
方法：一名33岁男子，有两年右上腹腹痛史，偶尔使用镇痛药缓解，但在过去的一个半月中恶化。考试显示出一种柔和，腹部不扩张，肝脏明显。实验室测试,包括病毒标志物和肿瘤标志物均正常。对比增强CT显示，肝脏III段有明确的椭圆形肿块，并伴有异质性增强，从而暂时诊断为HAML。患者接受了成功的整块切除术，没有术中或术后并发症。
■对于有症状的病例或不确定的活检，建议进行手术切除。由于复发的可能性和与其他恶性肿瘤的关联，需要严格的随访。
结论：HAML可表现为长期的非特异性腹部症状。CT成像有助于诊断脂肪组织丰富的病例。整块肿瘤切除在治疗症状表现方面被证明是安全有效的。
方法：一名33岁男子，有两年右上腹腹痛史，偶尔使用镇痛药缓解，但在过去的一个半月中恶化。考试显示出一种柔和，腹部不扩张，肝脏明显。实验室测试,包括病毒标志物和肿瘤标志物均正常。对比增强CT显示，肝脏III段有明确的椭圆形肿块，并伴有异质性增强，从而暂时诊断为HAML。患者接受了成功的整块切除术，没有术中或术后并发症。
■对于有症状的病例或不确定的活检，建议进行手术切除。由于复发的可能性和与其他恶性肿瘤的关联，需要严格的随访。
结论：HAML可表现为长期的非特异性腹部症状。CT成像有助于诊断脂肪组织丰富的病例。整块肿瘤切除在治疗症状表现方面被证明是安全有效的。
