PDF(Pubmed)
Abstract：
UNASSIGNED: Proper correction of spherical aberration using intraocular lenses requires precise selection of the sphericity of intraocular lens surfaces based on individual biometric data and corneal asphericity coefficient (Q value). This study aimed to determine and analyze the corneal Q value and its related factors among Saudi participants.
UNASSIGNED: In this cross-sectional study, normal right eyes of healthy Saudi participants aged 17 - 58 years who visited Al-Kahhal Medical Complex, Dammam, Saudi Arabia, were included. The Pentacam rotating Scheimpflug camera was used to determine the average Q value at 6-mm diameter. Q values were obtained from each quadrant (superior, nasal, inferior, and temporal) and two meridians (horizontal and vertical). Mean Q values of the anterior and posterior corneal surfaces were also obtained. Other factors including age, sex, refractive error, and central corneal radius were documented.
UNASSIGNED: Five hundred right eyes from 500 participants were included. The mean (standard deviation [SD]) (range) age was 27.2 (7.1) (18 - 58) years. The mean (SD) (range) Q value of 500 eyes was - 0.24 (0.10) (- 0.71 to + 0.09) anteriorly and - 0.16 (0.14) (- 0.70 to + 0.23) posteriorly, being significantly more prolate anteriorly (P < 0.05). The corneas were significantly more prolate in the nasal than in the temporal quadrant, in the superior than in the inferior quadrant, and in the horizontal than in the vertical meridian (all P < 0.05). There were statistically significant differences in anterior, nasal, temporal, inferior, horizontal, and vertical Q values among age groups (all P < 0.05) but not in the superior or posterior Q values (both P > 0.05). The corneas became less prolate with increasing age (P < 0.05). However, Q values were comparable between the sexes (all P > 0.05). There was no significant correlation between anterior (r = + 0.08; P = 0.095) or posterior (r = - 0.08; P = 0.092) Q value and spherical equivalent, but a significant trend was detected toward more prolate shape with increasing myopia in the temporal and inferior quadrants (r = + 0.19; P < 0.001, r = + 0.10; P = 0.022, respectively). There was a significant negligible correlation between the posterior Q value and central corneal radius (r = - 0.18; P < 0.001) but no significant correlation between the anterior Q value and central corneal radius (r = + 0.02; P = 0.673).
UNASSIGNED: Most corneas in this Saudi population were prolate in contour. Anterior corneal asphericity was positively correlated with age and was not significantly related to sex, refractive error, or central corneal radius. Further studies are needed to verify our preliminary findings.
UNASSIGNED: In this cross-sectional study, normal right eyes of healthy Saudi participants aged 17 - 58 years who visited Al-Kahhal Medical Complex, Dammam, Saudi Arabia, were included. The Pentacam rotating Scheimpflug camera was used to determine the average Q value at 6-mm diameter. Q values were obtained from each quadrant (superior, nasal, inferior, and temporal) and two meridians (horizontal and vertical). Mean Q values of the anterior and posterior corneal surfaces were also obtained. Other factors including age, sex, refractive error, and central corneal radius were documented.
UNASSIGNED: Five hundred right eyes from 500 participants were included. The mean (standard deviation [SD]) (range) age was 27.2 (7.1) (18 - 58) years. The mean (SD) (range) Q value of 500 eyes was - 0.24 (0.10) (- 0.71 to + 0.09) anteriorly and - 0.16 (0.14) (- 0.70 to + 0.23) posteriorly, being significantly more prolate anteriorly (P < 0.05). The corneas were significantly more prolate in the nasal than in the temporal quadrant, in the superior than in the inferior quadrant, and in the horizontal than in the vertical meridian (all P < 0.05). There were statistically significant differences in anterior, nasal, temporal, inferior, horizontal, and vertical Q values among age groups (all P < 0.05) but not in the superior or posterior Q values (both P > 0.05). The corneas became less prolate with increasing age (P < 0.05). However, Q values were comparable between the sexes (all P > 0.05). There was no significant correlation between anterior (r = + 0.08; P = 0.095) or posterior (r = - 0.08; P = 0.092) Q value and spherical equivalent, but a significant trend was detected toward more prolate shape with increasing myopia in the temporal and inferior quadrants (r = + 0.19; P < 0.001, r = + 0.10; P = 0.022, respectively). There was a significant negligible correlation between the posterior Q value and central corneal radius (r = - 0.18; P < 0.001) but no significant correlation between the anterior Q value and central corneal radius (r = + 0.02; P = 0.673).
UNASSIGNED: Most corneas in this Saudi population were prolate in contour. Anterior corneal asphericity was positively correlated with age and was not significantly related to sex, refractive error, or central corneal radius. Further studies are needed to verify our preliminary findings.
摘要：
■使用眼内透镜正确校正球面像差需要基于个体生物统计数据和角膜非球面系数（Q值）精确选择眼内透镜表面的球形度。本研究旨在确定和分析沙特参与者的角膜Q值及其相关因素。
■在这项横断面研究中，17-58岁的健康沙特参与者的正常右眼参观了Al-KahhalMedicalComplex，达曼,沙特阿拉伯,包括在内。Pentacam旋转Scheimpflug相机用于确定6毫米直径下的平均Q值。从每个象限获得Q值(上级，鼻部,劣等,和时间）和两个经络（水平和垂直）。还获得了角膜前表面和后表面的平均Q值。其他因素包括年龄,性别,屈光不正,并记录中央角膜半径。
■包括500名参与者的500只右眼。平均（标准差[SD]）（范围）年龄为27.2（7.1）（18-58）岁。500只眼的平均（SD）（范围）Q值向前-0.24（0.10）（-0.71至0.09），向后-0.16（0.14）（-0.70至0.23），显著延长(P<0.05)。角膜在鼻部明显比在颞部象限更加扩张，在上级比下象限，而在水平子午线比在垂直子午线（均P<0.05）。前路有统计学上的显著差异，鼻部,temporal,劣等,水平,各年龄组之间的垂直Q值（均P<0.05），但不在上或后Q值（均P>0.05）。随着年龄的增长，角膜扩张程度降低（P<0.05）。然而,性别之间的Q值相当（均P>0.05）。前(r=+0.08;P=0.095)或后(r=-0.08;P=0.092)Q值与等效球面无显著相关性,但是在颞侧和下象限中，随着近视的增加，发现了更扩张的趋势（r=0.19；P<0.001，r=0.10；P=0.022）。后Q值与中央角膜半径之间的相关性可以忽略不计（r=-0.18；P<0.001），而前Q值与中央角膜半径之间没有显着相关性（r=0.02；P=0.673）。
■这个沙特人口中的大多数角膜在轮廓上都是长的。角膜前非球面性与年龄呈正相关,与性别无显著相关性,屈光不正,或中央角膜半径。需要进一步的研究来验证我们的初步发现。
■在这项横断面研究中，17-58岁的健康沙特参与者的正常右眼参观了Al-KahhalMedicalComplex，达曼,沙特阿拉伯,包括在内。Pentacam旋转Scheimpflug相机用于确定6毫米直径下的平均Q值。从每个象限获得Q值(上级，鼻部,劣等,和时间）和两个经络（水平和垂直）。还获得了角膜前表面和后表面的平均Q值。其他因素包括年龄,性别,屈光不正,并记录中央角膜半径。
■包括500名参与者的500只右眼。平均（标准差[SD]）（范围）年龄为27.2（7.1）（18-58）岁。500只眼的平均（SD）（范围）Q值向前-0.24（0.10）（-0.71至0.09），向后-0.16（0.14）（-0.70至0.23），显著延长(P<0.05)。角膜在鼻部明显比在颞部象限更加扩张，在上级比下象限，而在水平子午线比在垂直子午线（均P<0.05）。前路有统计学上的显著差异，鼻部,temporal,劣等,水平,各年龄组之间的垂直Q值（均P<0.05），但不在上或后Q值（均P>0.05）。随着年龄的增长，角膜扩张程度降低（P<0.05）。然而,性别之间的Q值相当（均P>0.05）。前(r=+0.08;P=0.095)或后(r=-0.08;P=0.092)Q值与等效球面无显著相关性,但是在颞侧和下象限中，随着近视的增加，发现了更扩张的趋势（r=0.19；P<0.001，r=0.10；P=0.022）。后Q值与中央角膜半径之间的相关性可以忽略不计（r=-0.18；P<0.001），而前Q值与中央角膜半径之间没有显着相关性（r=0.02；P=0.673）。
■这个沙特人口中的大多数角膜在轮廓上都是长的。角膜前非球面性与年龄呈正相关,与性别无显著相关性,屈光不正,或中央角膜半径。需要进一步的研究来验证我们的初步发现。
