PDF(Pubmed)
Abstract：
Legionella pneumonia (LP) is a relatively uncommon yet well-known type of atypical community-acquired pneumonia (CAP). It is characterized by a rapid progression to severe pneumonia and can be easily misdiagnosed. In most patients, chest computed tomography (CT) showed patchy infiltration, which may progress to lobar infiltration or even lobar consolidation. While pulmonary cavities are commonly observed in immunocompromised patients with LP, they are considered rare in immunocompetent individuals. Herein, we present a case of LP in an immunocompetent patient with multiple cavities in both lungs. Pathogen detection was performed using metagenomic next-generation sequencing (mNGS). This case highlights the unusual radiographic presentation of LP in an immunocompetent patient and emphasizes the importance of considering LP as a possible diagnosis in patients with pulmonary cavities, regardless of their immune status. Furthermore, the timely utilization of mNGS is crucial for early pathogen identification, as it provides multiple benefits in enhancing the diagnosis and prognosis of LP patients.
摘要：
军团菌肺炎（LP）是一种相对罕见但众所周知的非典型社区获得性肺炎（CAP）。它的特点是快速发展为严重的肺炎，很容易被误诊。在大多数患者中，胸部计算机断层扫描（CT）显示斑片状浸润，这可能会进展到大叶浸润甚至大叶巩固。虽然肺腔通常在免疫受损的LP患者中观察到，它们在有免疫能力的个体中被认为是罕见的。在这里，我们介绍了一个有免疫能力的患者的LP病例，双肺有多个腔。使用宏基因组下一代测序(mNGS)进行病原体检测。该病例突出了免疫功能正常患者中LP的异常影像学表现，并强调了将LP视为肺腔患者可能诊断的重要性。不管他们的免疫状况如何。此外，及时利用mNGS对早期病原体识别至关重要，因为它在增强LP患者的诊断和预后方面提供了多种益处。
