PDF(Pubmed)
Abstract：
Euphorbia is a large genus of the Euphorbiaceae family. Around 250 species of the Euphorbia genus have been studied chemically and pharmacologically; different compounds have been isolated from these species, especially diterpenes and triterpenes. Several reports show that several species have anti-inflammatory activity, which can be attributed to the presence of diterpenes, such as abietanes, ingenanes, and lathyranes. In addition, it was found that some diterpenes isolated from different Euphorbia species have anti-cancer activity. In this review, we included compounds isolated from species of the Euphorbia genus with anti-inflammatory or cytotoxic effects published from 2018 to September 2023. The databases used for this review were Science Direct, Scopus, PubMed, Springer, and Google Scholar, using the keywords Euphorbia with anti-inflammatory or cytotoxic activity. In this review, 68 studies were collected and analyzed regarding the anti-inflammatory and anti-cancer activities of 264 compounds obtained from 36 species of the Euphorbia genus. The compounds included in this review are terpenes (95%), of which 68% are diterpenes, especially of the types ingenanes, abietanes, and triterpenes (approximately 15%).
摘要：
一品红是一品红科的一个大属。在化学和药理学上研究了大约250种大品藻属；从这些物种中分离出不同的化合物，尤其是二萜和三萜.一些报告显示，几种物种具有抗炎活性，这可以归因于二萜的存在，例如abietanes,ingenanes,和lathyranes。此外,发现从不同一品红种分离的一些二萜具有抗癌活性。在这次审查中,我们纳入了从2018年至2023年9月发表的具有抗炎或细胞毒性作用的一品红属物种中分离出的化合物.这篇综述使用的数据库是科学直接，Scopus,PubMed,Springer,和谷歌学者，使用具有抗炎或细胞毒性活性的关键字Euphorbia。在这次审查中,收集并分析了68项研究，这些研究涉及从36种大猩猩属物种获得的264种化合物的抗炎和抗癌活性。本综述中包括的化合物是萜烯(95%)，其中68%是二萜，尤其是ingenanes的类型，abietanes,和三萜(约15%)。
