Abstract：
Clinical management of Waldenström\'s Macroglobulinemia has seen major progress in the recent years, triggered by our improved understanding of the biology of the disease and the development of new therapies. Based on this there are multiple treatment options available for patients with WM ranging from classical immunochemotherapy to targeted approaches blocking key enzymes involved in lymphoma growth. This review summarizes our current knowledge about diagnostics and treatment of this rare but recurrent lymphoma subtype, which often presents a major clinical challenge in daily clinical life.
摘要：
Waldenström巨球蛋白血症的临床治疗近年来取得了重大进展，由我们对疾病生物学的理解和新疗法的发展引发。基于此,存在多种可用于患有WM的患者的治疗选择,从经典的免疫化疗到阻断参与淋巴瘤生长的关键酶的靶向方法。这篇综述总结了我们目前关于这种罕见但复发性淋巴瘤亚型的诊断和治疗的知识。这在日常临床生活中往往是一个重大的临床挑战。
