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Abstract：
BACKGROUND: Ovarian steroid cell tumors not otherwise specified (OSCT-NOS) are extremely rare ovarian sex cord stromal tumors, accounting for <0.1 % of all ovarian tumors. In 25 % of cases, they are asymptomatic leading to a delay in diagnosis. We, herein, report a singular case of OSCT-NOS diagnosed incidentally during the spread assessment of an invasive breast carcinoma of no special type (IBC-NOS). To the best of our knowledge, this is the first reported case of co-occurrence of OSCT-NOS and IBC-NOS. We aim to study the clinic-pathological characteristics of this rare tumor.
METHODS: A 56-years old postmenopausal female, with no previous medical history, was diagnosed with an invasive IBC-NOS. The tomography performed during the spread assessment of IBC-NOS showed a suspicious mass of the right ovary. Pelvic MRI revealed an ovarian solid T1 isointense and T2 hyperintense mass. The first evoked diagnosis was an ovarian metastasis of the IBC-NOS. The patient underwent bilateral salpingo-oophorectomy. On gross examination, an ovarian solid mass measuring 2,5x2cm, with a firm gray yellowish cut surface was noted. Microscopic examination and immunostaining concluded to OSCT-NOS and ruled out the diagnosis of an ovarian metastasis of IBC-NOS.
CONCLUSIONS: OSCT-NOS are rare neoplasms. Their diagnosis might be challenging especially in absence of hormonal symptoms. A better knowledge of this rare entities would enable early diagnosis.
METHODS: A 56-years old postmenopausal female, with no previous medical history, was diagnosed with an invasive IBC-NOS. The tomography performed during the spread assessment of IBC-NOS showed a suspicious mass of the right ovary. Pelvic MRI revealed an ovarian solid T1 isointense and T2 hyperintense mass. The first evoked diagnosis was an ovarian metastasis of the IBC-NOS. The patient underwent bilateral salpingo-oophorectomy. On gross examination, an ovarian solid mass measuring 2,5x2cm, with a firm gray yellowish cut surface was noted. Microscopic examination and immunostaining concluded to OSCT-NOS and ruled out the diagnosis of an ovarian metastasis of IBC-NOS.
CONCLUSIONS: OSCT-NOS are rare neoplasms. Their diagnosis might be challenging especially in absence of hormonal symptoms. A better knowledge of this rare entities would enable early diagnosis.
摘要：
背景：未特别说明的卵巢类固醇细胞肿瘤（OSCT-NOS）是极为罕见的卵巢性索间质肿瘤，占所有卵巢肿瘤的0.1%。在25%的案例中,它们无症状，导致诊断延迟。我们,在这里，报告1例OSCT-NOS在非特殊类型浸润性乳腺癌（IBC-NOS）的扩散评估中偶然诊断。据我们所知,这是首例同时出现OSCT-NOS和IBC-NOS的病例.我们的目的是研究这种罕见肿瘤的临床病理特征。
方法：一位56岁的绝经后女性，没有既往病史,被诊断为侵袭性IBC-NOS。在IBC-NOS扩散评估期间进行的断层扫描显示右侧卵巢可疑肿块。盆腔MRI显示卵巢实性T1等强度和T2高强度肿块。首次诱发诊断是IBC-NOS的卵巢转移。患者接受了双侧输卵管卵巢切除术。粗略检查，2,5x2cm的卵巢实性肿块,注意到具有坚硬的灰色淡黄色切割表面。显微镜检查和免疫染色得出OSCT-NOS的结论，并排除了IBC-NOS卵巢转移的诊断。
结论：OSCT-NOS是罕见肿瘤。他们的诊断可能具有挑战性，尤其是在没有激素症状的情况下。更好地了解这种罕见的实体将能够进行早期诊断。
方法：一位56岁的绝经后女性，没有既往病史,被诊断为侵袭性IBC-NOS。在IBC-NOS扩散评估期间进行的断层扫描显示右侧卵巢可疑肿块。盆腔MRI显示卵巢实性T1等强度和T2高强度肿块。首次诱发诊断是IBC-NOS的卵巢转移。患者接受了双侧输卵管卵巢切除术。粗略检查，2,5x2cm的卵巢实性肿块,注意到具有坚硬的灰色淡黄色切割表面。显微镜检查和免疫染色得出OSCT-NOS的结论，并排除了IBC-NOS卵巢转移的诊断。
结论：OSCT-NOS是罕见肿瘤。他们的诊断可能具有挑战性，尤其是在没有激素症状的情况下。更好地了解这种罕见的实体将能够进行早期诊断。
