关键词: cancer biomarkers cancer screening diagnostics epidemiology personalized approach prognosis

Mesh : Humans Precision Medicine / methods Prospective Studies Biomarkers Neoplasms / diagnosis therapy Biomarkers, Tumor Prognosis

来  源:   DOI:10.1515/dmpt-2023-0056

Abstract:
BACKGROUND: Cancer biomarkers have revolutionized the field of oncology by providing valuable insights into tumor changes and aiding in screening, diagnosis, prognosis, treatment prediction, and risk assessment. The emergence of \"omic\" technologies has enabled biomarkers to become reliable and accurate predictors of outcomes during cancer treatment.
BACKGROUND: In this review, we highlight the clinical utility of biomarkers in cancer identification and motivate researchers to establish a personalized/precision approach in oncology. By extending a multidisciplinary technology-based approach, biomarkers offer an alternative to traditional techniques, fulfilling the goal of cancer therapeutics to find a needle in a haystack.
UNASSIGNED: We target different forms of cancer to establish a dynamic role of biomarkers in understanding the spectrum of malignancies and their biochemical and molecular characterization, emphasizing their prospective contribution to cancer screening. Biomarkers offer a promising avenue for the early detection of human cancers and the exploration of novel technologies to predict disease severity, facilitating maximum survival and minimum mortality rates. This review provides a comprehensive overview of the potential of biomarkers in oncology and highlights their prospects in advancing cancer diagnosis and treatment.
摘要:
背景:癌症生物标志物通过提供对肿瘤变化的有价值的见解并帮助筛查,彻底改变了肿瘤学领域。诊断,预后,治疗预测,和风险评估。“组学”技术的出现使生物标志物成为癌症治疗期间结果的可靠和准确的预测因子。
背景:在这篇综述中,我们强调了生物标志物在癌症鉴定中的临床应用,并激励研究人员在肿瘤学中建立个性化/精确的方法.通过扩展基于多学科技术的方法,生物标志物提供了传统技术的替代方案,实现癌症治疗的目标是在大海捞针。
我们针对不同形式的癌症,以建立生物标志物在了解恶性肿瘤及其生化和分子特征方面的动态作用,强调他们对癌症筛查的前瞻性贡献。生物标志物为早期发现人类癌症和探索预测疾病严重程度的新技术提供了有希望的途径。促进最高生存率和最低死亡率。这篇综述全面概述了生物标志物在肿瘤学中的潜力,并强调了它们在推进癌症诊断和治疗方面的前景。
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