PDF(Pubmed)
Abstract：
UNASSIGNED: To explore the therapeutic effect of hyperbaric oxygen combined with subdural drilling and drainage (SDD) on subdural effusion type IV with intracranial infection in infant patients.
UNASSIGNED: This retrospective controlled study included 328 infant patients with subdural effusion type 4 with intracranial infection between January 2005 and January 2023. 178 patients were treated by hyperbaric oxygen combined with SDD (group A). 142 cases were treated with SDD (group B). 97 infants were only received hyperbaric oxygen (group C). Clinical outcomes, the control time of intracranial infection, complications, and the degree of brain re-expansion after 6 months of treatment were compared among the three groups. According to the comprehensive evaluation of treatment effectiveness and imaging results, it is divided into four levels: cured, significantly effective, improved, and ineffective.
UNASSIGNED: No patient died during follow-up. The three groups were similar regarding age, sex, the general information, and clinical symptoms (p > 0.05). All intracranial infections in the children were effectively controlled. There was no difference in infection control time between group A and group B, and there was no statistical significance. However, the control time of intracranial infection between the two groups was different from that of group C, which was statistically significant. Compared with group B and group C, the degree of brain re-expansion in group A has obvious advantages and significant differences. The effective rates of the three groups were 83.7%, 58.5%, and 56.7%, respectively. There were 28 cases of subcutaneous hydrops in group A and 22 cases of subcutaneous hydrops in group B after operation, and no other serious complications.
UNASSIGNED: The SDD is safe and effective for infant patients with intracranial infections through fluid replacement and intrathecal antibacterial. Hyperbaric oxygen is effective as an adjuvant therapy to promote brain re-expansion.
UNASSIGNED: This retrospective controlled study included 328 infant patients with subdural effusion type 4 with intracranial infection between January 2005 and January 2023. 178 patients were treated by hyperbaric oxygen combined with SDD (group A). 142 cases were treated with SDD (group B). 97 infants were only received hyperbaric oxygen (group C). Clinical outcomes, the control time of intracranial infection, complications, and the degree of brain re-expansion after 6 months of treatment were compared among the three groups. According to the comprehensive evaluation of treatment effectiveness and imaging results, it is divided into four levels: cured, significantly effective, improved, and ineffective.
UNASSIGNED: No patient died during follow-up. The three groups were similar regarding age, sex, the general information, and clinical symptoms (p > 0.05). All intracranial infections in the children were effectively controlled. There was no difference in infection control time between group A and group B, and there was no statistical significance. However, the control time of intracranial infection between the two groups was different from that of group C, which was statistically significant. Compared with group B and group C, the degree of brain re-expansion in group A has obvious advantages and significant differences. The effective rates of the three groups were 83.7%, 58.5%, and 56.7%, respectively. There were 28 cases of subcutaneous hydrops in group A and 22 cases of subcutaneous hydrops in group B after operation, and no other serious complications.
UNASSIGNED: The SDD is safe and effective for infant patients with intracranial infections through fluid replacement and intrathecal antibacterial. Hyperbaric oxygen is effective as an adjuvant therapy to promote brain re-expansion.
摘要：
■探讨高压氧联合硬膜下钻孔引流术(SDD)治疗小儿颅内感染的IV型硬膜下积液的疗效。
■这项回顾性对照研究包括2005年1月至2023年1月间发生颅内感染的328例4型硬膜下积液婴儿患者。178例患者采用高压氧联合SDD治疗(A组)。142例接受SDD治疗(B组)。97例婴儿仅接受高压氧（C组）。临床结果,颅内感染的控制时间，并发症,比较3组患者治疗6个月后的脑再扩张程度。根据治疗效果和影像学结果的综合评价,它分为四个级别:治愈，显著有效,改进,和无效。
■随访期间无患者死亡。三组的年龄相似，性别,一般信息，临床症状(p>0.05)。患儿颅内感染均得到有效控制。A组与B组感染控制时间无差异,没有统计学意义。然而,两组颅内感染的控制时间与C组不同,具有统计学意义。与B组和C组比较,A组脑再扩张程度具有明显优势,差异显著。三组有效率均为83.7%,58.5%,56.7%，分别。术后A组28例皮下积液,B组22例皮下积液。无其他严重并发症。
■SDD通过补液和鞘内抗菌对颅内感染的婴儿患者安全有效。高压氧作为促进脑再扩张的辅助疗法是有效的。
■这项回顾性对照研究包括2005年1月至2023年1月间发生颅内感染的328例4型硬膜下积液婴儿患者。178例患者采用高压氧联合SDD治疗(A组)。142例接受SDD治疗(B组)。97例婴儿仅接受高压氧（C组）。临床结果,颅内感染的控制时间，并发症,比较3组患者治疗6个月后的脑再扩张程度。根据治疗效果和影像学结果的综合评价,它分为四个级别:治愈，显著有效,改进,和无效。
■随访期间无患者死亡。三组的年龄相似，性别,一般信息，临床症状(p>0.05)。患儿颅内感染均得到有效控制。A组与B组感染控制时间无差异,没有统计学意义。然而,两组颅内感染的控制时间与C组不同,具有统计学意义。与B组和C组比较,A组脑再扩张程度具有明显优势,差异显著。三组有效率均为83.7%,58.5%,56.7%，分别。术后A组28例皮下积液,B组22例皮下积液。无其他严重并发症。
■SDD通过补液和鞘内抗菌对颅内感染的婴儿患者安全有效。高压氧作为促进脑再扩张的辅助疗法是有效的。
