PDF(Pubmed)
Abstract：
UNASSIGNED: In an era of minimally invasive and rapid diagnostic technologies, fine-needle aspiration cytology (FNAC) is most useful when it comes to patients with lymphadenopathies especially of the cervical region. Liquid-based cytology (LBC) is an alternative processing method which is used for both gynecological and non-gynecological samples. Because of the remarkable advantages of LBC smears in gynecological samples, nowadays, many studies have been done to assess its utility in various other lesions. Hereby, with the help of this study, we would like to evaluate the efficiency of LBC smears in comparison to conventional FNAC smears conventional smears (CS) on lymph node aspirates.
UNASSIGNED: A retrospective study was done over a 1-year period in which 253 cases of lymph node aspirates were included in the study. The slides were prepared using standard conventional and LBC techniques and compared for adequacy, cellularity, cell architecture, necrosis, background debris, presence of cells in monolayer sheets, and nuclear/cytoplasmic details.
UNASSIGNED: Of the total 253 cases, 171 (67.6%) were and 67 (26.5%) were diagnosed as non-neoplastic and malignant, respectively. Although the LBC smears were useful in the diagnosis of malignant cases, they did pose some challenges especially in the non-neoplastic lymph node aspirates due to loss of the background necrosis. In addition, the cellular yield in LBC smears was low in comparison to CS.
UNASSIGNED: LBC smears from lymph node aspirates results in better diagnostic accuracy for malignant cases due to better cellular and nuclear details. However, for non-neoplastic etiology, it should not be considered better than CS as loss of the background necrosis and inflammation may result in an incorrect diagnosis.
UNASSIGNED: A retrospective study was done over a 1-year period in which 253 cases of lymph node aspirates were included in the study. The slides were prepared using standard conventional and LBC techniques and compared for adequacy, cellularity, cell architecture, necrosis, background debris, presence of cells in monolayer sheets, and nuclear/cytoplasmic details.
UNASSIGNED: Of the total 253 cases, 171 (67.6%) were and 67 (26.5%) were diagnosed as non-neoplastic and malignant, respectively. Although the LBC smears were useful in the diagnosis of malignant cases, they did pose some challenges especially in the non-neoplastic lymph node aspirates due to loss of the background necrosis. In addition, the cellular yield in LBC smears was low in comparison to CS.
UNASSIGNED: LBC smears from lymph node aspirates results in better diagnostic accuracy for malignant cases due to better cellular and nuclear details. However, for non-neoplastic etiology, it should not be considered better than CS as loss of the background necrosis and inflammation may result in an incorrect diagnosis.
摘要：
■在微创和快速诊断技术的时代，细针穿刺细胞学（FNAC）是最有用的，当它涉及到有淋巴结病变的患者，尤其是宫颈区域。液基细胞学(LBC)是用于妇科和非妇科样品的替代处理方法。由于LBC涂片在妇科样本中的显著优势，如今,已经进行了许多研究来评估其在各种其他病变中的效用。特此,在这项研究的帮助下，我们想评估LBC涂片与常规FNAC涂片在淋巴结吸出物上的常规涂片（CS）相比的效率。
■进行了为期1年的回顾性研究，其中253例淋巴结抽吸物被纳入研究。使用标准常规技术和LBC技术制备载玻片，并比较其充分性。cellularity,细胞架构，坏死,背景碎片,单层细胞的存在，和核/细胞质细节。
■在总共253个案例中，171（67.6％）和67（26.5％）被诊断为非肿瘤性和恶性，分别。尽管LBC涂片对恶性病例的诊断有用，它们确实带来了一些挑战，尤其是在非肿瘤淋巴结抽吸物中，由于背景坏死的丧失。此外,与CS相比，LBC涂片中的细胞产量较低。
■来自淋巴结抽吸物的LBC涂片由于更好的细胞和核细节而对恶性病例具有更好的诊断准确性。然而,对于非肿瘤性病因，不应将其视为优于CS，因为背景坏死和炎症的丢失可能导致错误的诊断。
■进行了为期1年的回顾性研究，其中253例淋巴结抽吸物被纳入研究。使用标准常规技术和LBC技术制备载玻片，并比较其充分性。cellularity,细胞架构，坏死,背景碎片,单层细胞的存在，和核/细胞质细节。
■在总共253个案例中，171（67.6％）和67（26.5％）被诊断为非肿瘤性和恶性，分别。尽管LBC涂片对恶性病例的诊断有用，它们确实带来了一些挑战，尤其是在非肿瘤淋巴结抽吸物中，由于背景坏死的丧失。此外,与CS相比，LBC涂片中的细胞产量较低。
■来自淋巴结抽吸物的LBC涂片由于更好的细胞和核细节而对恶性病例具有更好的诊断准确性。然而,对于非肿瘤性病因，不应将其视为优于CS，因为背景坏死和炎症的丢失可能导致错误的诊断。
