关键词: Cognitive impairment Dementia Overview of systematic reviews Sleep disorder

来  源:   DOI:10.1007/s41105-022-00439-9   PDF(Pubmed)

Abstract:
Sleep disorders frequently result in poor memory, attention deficits, as well as a worse prognosis for neurodegenerative changes, such as Alzheimer\'s disease. The purpose of this study is to investigate the impact of sleep disorders on cognition. We screened four databases for all meta-analyses and systematic reviews from the establishment through March 2022. We have carried out quality evaluation and review the eligible systematic reviews. Evidence grading and quality assessment were performed on 22 eligible articles. Sleep deprivation primarily affects simple attention, complex attention, and working memory in cognition and alertness. The moderate-to-high-quality evidence proves optimal sleep time as 7-8 h. Sleep time outside this range increases the risk of impaired executive function, non-verbal memory, and working memory. Sleep-related breathing disorders is more likely to cause mild cognitive impairment and affects several cognitive domains. In older adults, insomnia primarily affects working memory, episodic memory, inhibitory control, cognitive flexibility, problem-solving, operational ability, perceptual function, alertness, and complex attention, and maintaining sensitivity. Sleep disturbances significantly impair cognitive function, and early detection and intervention may be critical steps in reducing poor prognosis. A simple neuropsychological memory test could be used to screen people with sleep disorders for cognitive impairment.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s41105-022-00439-9.
摘要:
睡眠障碍经常导致记忆力差,注意力缺陷,以及神经退行性变化的预后较差,如老年痴呆症。目的探讨睡眠障碍对认知的影响。我们筛选了四个数据库,从建立到2022年3月的所有荟萃分析和系统评价。我们已经进行了质量评估,并对符合条件的系统评价进行了审查。对22篇符合条件的文章进行了证据分级和质量评估。睡眠不足主要影响简单的注意力,复杂的注意力,以及认知和警觉性方面的工作记忆。中等至高质量的证据证明最佳睡眠时间为7-8小时。超出此范围的睡眠时间会增加执行功能受损的风险,非语言记忆,和工作记忆。与睡眠相关的呼吸障碍更有可能导致轻度认知障碍,并影响多个认知领域。在老年人中,失眠主要影响工作记忆,情景记忆,抑制控制,认知灵活性,解决问题,作战能力,感知功能,机敏,和复杂的注意力,保持灵敏度。睡眠障碍显著损害认知功能,早期发现和干预可能是减少不良预后的关键步骤。一个简单的神经心理记忆测试可以用来筛查睡眠障碍患者的认知障碍。
在线版本包含补充材料,可在10.1007/s41105-022-00439-9获得。
公众号