UNASSIGNED: We present the case of a 32-year-old man with MADD who was on a high-carbohydrate diet for >30 years and exhibited symptoms resembling diabetic ketoacidosis. He presented with polydipsia, polyuria, and weight loss with a decrease in body mass index from 31 to 25 kg/m2 over 2 months. Laboratory tests revealed a HbA1c level of 13.9%; however, the patient did not show metabolic acidosis but only mild ketosis.
UNASSIGNED: This report emphasizes the potential association between long-term adherence to high-carbohydrate dietary therapy and T2DM development. Moreover, this case underscores the difficulty of detecting diabetic ketosis in patients with FAODs such as MADD due to their inability to produce ketone bodies. These findings warrant further research of the long-term complications associated with this diet as well as warning of the potential progression of diabetes in patients with FAODs such as MADD.
■我们介绍了一例32岁的MADD患者,该患者接受高碳水化合物饮食30年以上,并表现出类似糖尿病酮症酸中毒的症状。他表现为多饮,多尿,和体重减轻,体重指数在2个月内从31下降到25kg/m2。实验室检测显示HbA1c水平为13.9%;然而,患者未出现代谢性酸中毒,仅出现轻度酮症.
■本报告强调了长期坚持高碳水化合物饮食治疗与T2DM发展之间的潜在关联。此外,该病例强调了由于MADD等FAOD患者无法产生酮体而难以检测糖尿病酮症.这些发现需要进一步研究与这种饮食相关的长期并发症,并警告患有FAOD(如MADD)的患者糖尿病的潜在进展。