Abstract：
This study presents a critical analysis of complications following cranioplasty (CP) after decompressive hemicraniectomy, focusing on autologous, polymethylmethacrylate (PMMA), and computer-aided design (CAD) implants. The analysis encompasses a retrospective bicenter assessment, evaluating factors influencing surgical outcomes and emphasizing the significance of material selection in minimizing postoperative complications. The study\'s comprehensive examination of complication rates associated with various implant materials contributes significantly to understanding CP outcomes. While polymethylmethacrylate (PMMA) and autologous bone flaps (ABFs) exhibited higher rates of surgical site infection (SSI) and explantation, a meta-analysis revealed a contrasting lower infection rate for polyether ether ketone (PEEK) implants. The study underscores the critical role of material selection in mitigating postoperative complications. Despite its strengths, the study\'s retrospective design, reliance on data from two centers, and limited sample size pose limitations. Future research should prioritize prospective, multicenter studies with standardized protocols to enhance diagnostic accuracy and treatment efficacy in CP procedures.
摘要：
本研究对去骨瓣减压切除术后颅骨成形术（CP）后的并发症进行了关键分析，专注于自体，聚甲基丙烯酸甲酯(PMMA),和计算机辅助设计（CAD）植入物。分析包括回顾性双中心评估，评估影响手术结果的因素，并强调材料选择在减少术后并发症方面的重要性。该研究对各种植入材料相关的并发症发生率进行全面检查，有助于了解CP结果。虽然聚甲基丙烯酸甲酯（PMMA）和自体骨瓣（ABFs）表现出更高的手术部位感染率（SSI）和外植术，一项荟萃分析显示,聚醚醚酮(PEEK)植入物的感染率相对较低.该研究强调了材料选择在减轻术后并发症中的关键作用。尽管它的优势，这项研究的回顾性设计，依赖两个中心的数据，有限的样本量构成了限制。未来的研究应该优先考虑前瞻性的，具有标准化方案的多中心研究，以提高CP程序的诊断准确性和治疗效果。
