关键词: Food safety Fungal interactions Metabolomic profiling Sustainable agriculture Toxin glycosylation

Mesh : T-2 Toxin / metabolism analogs & derivatives Fusarium / metabolism Trichoderma / metabolism Glycosylation Edible Grain / metabolism Glucosides / metabolism

来  源:   DOI:10.1038/s41598-024-55920-x   PDF(Pubmed)

Abstract:
The present study assessed the ability of Trichoderma to combat F. sporotrichioides, focusing on their antagonistic properties. Tests showed that Trichoderma effectively inhibited F. sporotrichioides mycelial growth, particularly with T. atroviride strains. In co-cultures on rice grains, Trichoderma almost completely reduced the biosynthesis of T-2 and HT-2 toxins by Fusarium. T-2 toxin-α-glucoside (T-2-3α-G), HT-2 toxin-α-glucoside (HT-2-3α-G), and HT-2 toxin-β-glucoside (HT-2-3β-G) were observed in the common culture medium, while these substances were not present in the control medium. The study also revealed unique metabolites and varying metabolomic profiles in joint cultures of Trichoderma and Fusarium, suggesting complex interactions. This research offers insights into the processes of biocontrol by Trichoderma, highlighting its potential as a sustainable solution for managing cereal plant pathogens and ensuring food safety.
摘要:
本研究评估了木霉对抗孢霉病的能力,专注于它们的拮抗性质。试验表明,木霉能有效抑制孢霉病菌菌丝生长,特别是T.atroviride菌株。在稻谷的共培养中,木霉几乎完全减少镰刀菌对T-2和HT-2毒素的生物合成。T-2毒素-α-葡萄糖苷(T-2-3α-G),HT-2毒素-α-葡萄糖苷(HT-2-3α-G),在普通培养基中观察到HT-2毒素-β-葡萄糖苷(HT-2-3β-G),而这些物质不存在于对照培养基中。该研究还揭示了木霉属和镰刀菌的联合培养物中独特的代谢物和不同的代谢组学特征,暗示复杂的相互作用。这项研究提供了对木霉生物防治过程的见解,强调其作为管理谷物植物病原体和确保食品安全的可持续解决方案的潜力。
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