Mesh : Humans Male Kidney / metabolism diagnostic imaging Female Technetium Tc 99m Dimercaptosuccinic Acid / metabolism pharmacokinetics Adult Middle Aged Technetium Tc 99m Mertiatide / metabolism Biological Transport Radionuclide Imaging Aged Radiopharmaceuticals / pharmacokinetics

来  源:   DOI:10.1097/MNM.0000000000001831

Abstract:
OBJECTIVE: The purpose of this study is to compare the value of absolute renal uptake (ARU %) in patients by using Tc-99m MAG-3 and Tc-99m DMSA scan.
METHODS: Absolute renal uptake is calculated using Tc-99m MAG-3 and Tc-99m DMSA in renal scintigraphy, Itoh and Tauex kidney depth methods used, respectively. n = 40 adult patients of both genders were included. All patients underwent Tc-99m MAG-3 and Tc-99m DMSA, respectively.
RESULTS: The values of ARU (%) were calculated separately in selected patients n = 40, (left = 17, right = 23 normal functioning kidneys) by MAG-3 and DMSA. Absolute renal uptake (%) of Tc-99m MAG-3 in left kidneys was found to be 15.2 ± 3.4, with spilt renal function 79.2 ± 14.7 and ARU (%) in right kidneys 16.2 ± 3.4 with spilt renal function 77.5 ± 19. Absolute renal uptake of Tc-99m DMSA in left kidneys was 17.5 ± 3.2 and in right kidneys 17.9 ± 4.5 with spilt renal function 81.8 ± 10.7 and 79.3 ± 13.8 for left and right kidney, respectively. Statistical analysis showed strong Pearson correlation.
CONCLUSIONS: Absolute renal uptake % was found to be more reliable in cases of bilateral compromised kidneys. ARU (%) calculated by Tc-99m MAG-3 solely can be used as predictor of renal function. The use of Tc-99m MAG-3 has more advantages than Tc-99m DMSA alone in renal scintigraphy as dynamic scintigraphy gives less radiation burden to patient, more information regarding renal function, and shorter stay time at hospital in comparison to static renal imaging. SRF % is less reliable than ARU (%).
摘要:
目的:本研究的目的是通过使用Tc-99mMAG-3和Tc-99mDMSA扫描比较患者的绝对肾摄取值(ARU%)。
方法:在肾脏闪烁显像中使用Tc-99mMAG-3和Tc-99mDMSA计算绝对肾脏摄取,使用伊藤和Tauex肾脏深度方法,分别。包括n=40名两种性别的成年患者。所有患者均接受Tc-99mMAG-3和Tc-99mDMSA,分别。
结果:通过MAG-3和DMSA分别计算了选定患者n=40(左=17,右=23正常功能肾脏)的ARU(%)值。左肾Tc-99mMAG-3的绝对肾摄取(%)为15.2±3.4,肾功能溢出79.2±14.7,右肾ARU(%)为16.2±3.4,肾功能溢出77.5±19。左肾Tc-99mDMSA的肾脏绝对摄取为17.5±3.2,右肾为17.9±4.5,左右肾的肾功能分别为81.8±10.7和79.3±13.8,分别。统计学分析显示Pearson相关性强。
结论:在双侧肾脏受损的情况下,绝对肾脏摄取百分比更可靠。由Tc-99mMAG-3单独计算的ARU(%)可以用作肾功能的预测因子。在肾闪烁显像中,使用Tc-99mMAG-3比单独使用Tc-99mDMSA更具优势,因为动态闪烁显像对患者的辐射负担较小。更多关于肾功能的信息,与静态肾脏成像相比,住院时间更短。SRF%不如ARU(%)可靠。
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