PDF(Pubmed)
Abstract：
Thyroid cancer is a common malignancy worldwide, and its incidence is increasing rapidly, especially in women. In the majority of cases, it presents solely with a palpable neck swelling. Less commonly, the disease manifests with symptoms of advanced stages, such as superior vena cava (SVC) obstruction and indications of recurrent laryngeal nerve invasion. Anaplastic thyroid cancer is a rare variant of thyroid cancer and is considered to have one of the poorest prognoses, and its diagnosis and treatment are challenging. On the other hand, undifferentiated pleomorphic sarcoma is a differential diagnosis with many clinical and histological similarities, which can only be confirmed through immunohistochemical studies. We herein report a challenging case of a 69-year-old female patient who presented with obstructive symptoms, diagnosed with anaplastic thyroid cancer exhibiting unusual clinical and histological features.
摘要：
甲状腺癌是世界范围内常见的恶性肿瘤,它的发病率正在迅速增加，尤其是女性。在大多数情况下,它只表现为明显的颈部肿胀。不太常见，这种疾病表现为晚期症状，例如上腔静脉（SVC）阻塞和喉返神经侵犯的指征。间变性甲状腺癌是甲状腺癌的一种罕见变种，被认为是预后最差的一种，其诊断和治疗具有挑战性。另一方面,未分化多形性肉瘤是一种具有许多临床和组织学相似性的鉴别诊断，这只能通过免疫组织化学研究来证实。我们在此报告了一个有挑战性的病例，一名69岁的女性患者出现阻塞性症状，诊断为甲状腺未分化癌，表现出异常的临床和组织学特征。
