PDF(Pubmed)
Abstract：
UNASSIGNED: We present a case of a patient with osteogenesis imperfecta (OI) and keratoglobus (KG) who had a near-total rupture of Descemet\'s membrane followed by spontaneous corneal clearing. This case is unique in that it demonstrates the potentially excellent outcome of conservative treatment for Descemet\'s rupture in patients with KG and illustrates the impressive migratory potential of healthy endothelial cells.
UNASSIGNED: An 11-year-old girl with OI and KG who had rupture and near-total detachment of Descemet\'s membrane presented for evaluation. This was managed conservatively and resulted in the eventual spontaneous clearing of the cornea. A similar process happened in the fellow eye some years later. Given the result of conservative management originally, the patient was once again treated conservatively, with significant improvement in corneal edema and visual acuity.
UNASSIGNED: Given the size of the ruptures, this case highlights the dynamic nature of the corneal endothelium and provides an extreme example of the migratory potential of corneal endothelial cells.
UNASSIGNED: An 11-year-old girl with OI and KG who had rupture and near-total detachment of Descemet\'s membrane presented for evaluation. This was managed conservatively and resulted in the eventual spontaneous clearing of the cornea. A similar process happened in the fellow eye some years later. Given the result of conservative management originally, the patient was once again treated conservatively, with significant improvement in corneal edema and visual acuity.
UNASSIGNED: Given the size of the ruptures, this case highlights the dynamic nature of the corneal endothelium and provides an extreme example of the migratory potential of corneal endothelial cells.
摘要：
■我们介绍了一例成骨不全症（OI）和角膜角球（KG）患者，其Descemet膜几乎完全破裂，然后自发角膜清除。这种情况是独特的，因为它证明了KG患者保守治疗Descemet破裂的潜在优异结果，并说明了健康内皮细胞令人印象深刻的迁移潜力。
■一名患有OI和KG的11岁女孩，Descemet膜破裂并几乎完全脱离，以进行评估。这是保守管理的，导致角膜最终自发清除。几年后，同伴的眼睛也发生了类似的过程。鉴于最初保守管理的结果，患者再次得到保守治疗，角膜水肿和视力明显改善。
■考虑到破裂的大小，该病例强调了角膜内皮的动态性质，并提供了角膜内皮细胞迁移潜力的极端例子。
■一名患有OI和KG的11岁女孩，Descemet膜破裂并几乎完全脱离，以进行评估。这是保守管理的，导致角膜最终自发清除。几年后，同伴的眼睛也发生了类似的过程。鉴于最初保守管理的结果，患者再次得到保守治疗，角膜水肿和视力明显改善。
■考虑到破裂的大小，该病例强调了角膜内皮的动态性质，并提供了角膜内皮细胞迁移潜力的极端例子。
