关键词: endometrial carcinoma fertility preservation in vitro fertilization-embryo transfer pregnancy outcome

来  源:   DOI:10.2147/IJWH.S441984   PDF(Pubmed)

Abstract:
Preserving fertility is a vital concern for young women diagnosed with endometrial carcinoma. The clinical management of such patients is often disappointing. It is rare to have two consecutive successful pregnancies. We present a child-bearing-age woman who underwent fertility preservation therapy due to endometrial carcinoma. Following fertility preservation therapy, she underwent in vitro fertilization and embryo transfer. After receiving her first fresh embryo transfer, she successfully conceived and gave birth to a healthy child. Two years after the first embryo transfer and regular follow-up, she had another frozen embryo transfer of two cleavage embryos and successfully gave birth to another healthy baby. After the delivery of her second child, she underwent surgical treatment for endometrial carcinoma. For endometrial carcinoma patients who intend to preserve fertility, high-quality long-term follow-up and personalized treatment are necessary.
In this case report, we share the story of one young woman who had endometrial cancer but desired to have children. She received fertility-sparing treatment and in vitro fertilization to increase her chances of conceiving. She successfully delivered a healthy child after the first embryo transfer. Two years later, she had another healthy child through a second frozen embryo transfer. Rigorous monitoring showed no cancer recurrence throughout the entire treatment. There are currently few reported cases of a patient with endometrial cancer successfully and safely giving birth twice through assisted reproductive technology. This case report emphasizes that, with personalized treatment and monitoring, endometrial cancer patients can have multiple pregnancies safely. In summary, this case report brings hope to young women with early-stage endometrial cancer who aspire to become mothers. With the right support, they can overcome the challenges of cancer and have their own babies.
摘要:
对于诊断为子宫内膜癌的年轻女性来说,保持生育能力是至关重要的。此类患者的临床管理通常令人失望。很少有连续两次成功怀孕。我们介绍了一名育龄妇女,她因子宫内膜癌而接受了生育能力保留治疗。保留生育力治疗后,她接受了体外受精和胚胎移植。在接受了她的第一次新鲜胚胎移植后,她成功怀孕并生下了一个健康的孩子。第一次胚胎移植和定期随访两年后,她又进行了两个卵裂胚胎的冷冻胚胎移植,并成功生下了另一个健康的婴儿。在她的第二个孩子出生后,她接受了子宫内膜癌的手术治疗。对于打算保留生育能力的子宫内膜癌患者,高质量的长期随访和个性化治疗是必要的。
在这种情况下,我们分享一个年轻女性的故事,她患有子宫内膜癌,但想要孩子。她接受了保留生育能力的治疗和体外受精,以增加受孕的机会。她在第一次胚胎移植后成功分娩了一个健康的孩子。两年后,她通过第二次冷冻胚胎移植又有了一个健康的孩子。严格的监测显示在整个治疗过程中没有癌症复发。目前很少报道子宫内膜癌患者通过辅助生殖技术成功安全分娩两次。本病例报告强调,通过个性化的治疗和监测,子宫内膜癌患者可以安全地进行多胎妊娠.总之,该病例报告为渴望成为母亲的早期子宫内膜癌年轻女性带来了希望。有了正确的支持,他们可以克服癌症的挑战,有自己的孩子。
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