Abstract：
BACKGROUND: In recent years, there has been an increase of studies dedicated to cognitive rehabilitation in patients with multiple sclerosis (MS); however, few of these analyze the impact on such variables as cognitive reserve. The study aims to explore the effects of a cognitive rehabilitation program comprising a combination of cognitive and physical exercises, as well as group sessions to improve cognitive performance, emotional state, and cognitive reserve index.
METHODS: Fifty patients with MS were subdivided into 2 groups: the control group, which performed aerobic exercise (n=25), and the experimental group (n=25), which participated in the integrated cognitive rehabilitation program (ICRP). All participants were evaluated 3 times (baseline, post-treatment, and long-term) with the Brief Repeatable Battery of Neuropsychological Tests, Cognitive Reserve Scale, Beck Depression Inventory, and a scale evaluating trait and state anxiety.
RESULTS: Compared with the control group, patients in the experimental group showed improvements in cognitive function, with significant changes in measures of information processing speed, attention, memory, cognitive reserve index, and long-term mood.
CONCLUSIONS: The ICRP was effective in improving cognitive and emotional function in MS, and increased the cognitive reserve index.
METHODS: Fifty patients with MS were subdivided into 2 groups: the control group, which performed aerobic exercise (n=25), and the experimental group (n=25), which participated in the integrated cognitive rehabilitation program (ICRP). All participants were evaluated 3 times (baseline, post-treatment, and long-term) with the Brief Repeatable Battery of Neuropsychological Tests, Cognitive Reserve Scale, Beck Depression Inventory, and a scale evaluating trait and state anxiety.
RESULTS: Compared with the control group, patients in the experimental group showed improvements in cognitive function, with significant changes in measures of information processing speed, attention, memory, cognitive reserve index, and long-term mood.
CONCLUSIONS: The ICRP was effective in improving cognitive and emotional function in MS, and increased the cognitive reserve index.
摘要：
背景：近年来，多发性硬化症（MS）患者的认知康复研究有所增加；然而，其中很少分析对认知储备等变量的影响。该研究旨在探索认知康复计划的效果，该计划包括认知和体育锻炼的组合，以及提高认知能力的小组会议，情绪状态,和认知储备指数。
方法：将50例MS患者分为2组：对照组，进行有氧运动(n=25)，和实验组（n=25），参加了综合认知康复计划（ICRP）。所有参与者均接受3次评估（基线，治疗后,和长期）与简短的可重复的神经心理学测试电池，认知储备量表，贝克抑郁量表，以及评估特质和状态焦虑的量表。
结果：与对照组相比，实验组患者的认知功能有所改善，随着信息处理速度的显著变化，注意,记忆,认知储备指数，和长期的情绪。
结论：ICRP可有效改善MS的认知和情绪功能，提高了认知储备指数。
方法：将50例MS患者分为2组：对照组，进行有氧运动(n=25)，和实验组（n=25），参加了综合认知康复计划（ICRP）。所有参与者均接受3次评估（基线，治疗后,和长期）与简短的可重复的神经心理学测试电池，认知储备量表，贝克抑郁量表，以及评估特质和状态焦虑的量表。
结果：与对照组相比，实验组患者的认知功能有所改善，随着信息处理速度的显著变化，注意,记忆,认知储备指数，和长期的情绪。
结论：ICRP可有效改善MS的认知和情绪功能，提高了认知储备指数。
