Mesh : Humans Colonic Pouches / adverse effects Proctocolectomy, Restorative / adverse effects methods Postoperative Complications / etiology epidemiology physiopathology Defecation / physiology Anal Canal / surgery physiopathology

来  源:   DOI:10.1097/DCR.0000000000003332

Abstract:
BACKGROUND: The IPAA is a boon to patients needing proctocolectomy but maintains per anal function through anatomic and physiologic compromises. The state of pouch function is hard to define because pouch anatomy is not normal and pouch physiology is a distortion of normal defecation. Patients with pouches develop multiple symptoms: some are expected, some are disease related, and some are the result of surgical complications. It is important to understand the cause of pouch-related symptoms so that appropriate management is offered.
OBJECTIVE: The study aimed to review pouch symptoms and discuss their likely cause, review the literature on pouch function and dysfunction, and provide clarity to clear the confusion.
METHODS: PubMed and Cochrane databases were searched using the terms \"ileoanal pouch function\" and \"ileoanal pouch dysfunction.\"
METHODS: From 1983 to 2023, 553 articles related to \"ileoanal pouch function\" and 178 related to \"ileoanal pouch dysfunction\" were reviewed. Nine studies appeared under both headings. Case studies, duplicate publications, and articles concerning pouch diseases were excluded.
METHODS: Definitions of pouch function and dysfunction, methods of describing and scoring symptoms, and understanding of expected changes in pouch function given the nature of the surgery.
RESULTS: Twenty-seven studies were reviewed from the ileoanal pouch dysfunction search and 38 from ileoanal pouch function. Three studies tried to define normal pouch function, 10 attempted to measure pouch function, and 4 aimed to score pouch function. Only 3 studies addressed pouch physiology.
CONCLUSIONS: A full discussion of pouch dysfunction is limited by the lack of studies focussing on the anatomic and physiologic consequences of turning the terminal ileum into an organ of storage.
CONCLUSIONS: Most studies of pouch function and dysfunction do not consider expected changes in the physiology of defecation that follow restorative proctocolectomy. Thus, most studies of pouch function produce conclusions that lack an important dimension. See video from symposium.
摘要:
背景:回肠袋-肛门吻合术对需要直肠结肠切除术的患者是一个福音,但通过解剖和生理方面的妥协来维持肛门功能。囊袋功能的状态很难定义,因为囊袋解剖结构不正常,并且囊袋生理机能是正常排便的扭曲。有包袋的患者会出现多种症状;有些是预期的,一些疾病相关的,和一些手术并发症的结果。重要的是要了解囊袋相关症状的原因,以便提供适当的管理。
目的:回顾眼袋症状并讨论其可能的原因。回顾有关囊袋功能和功能障碍的文献,并澄清混淆。
方法:PubMed和Cochrane数据库使用术语“回肠袋功能”和“回肠袋功能障碍”进行搜索。
方法:回顾了1983年至2023年来自“回肠袋功能”的553篇文章和来自“回肠袋功能障碍”的178篇文章。九项研究出现在两个标题下。案例研究,重复出版物,有关囊袋疾病的文章被排除在外。
方法:囊袋功能和功能障碍的定义,描述和评分症状的方法,考虑到手术的性质,了解囊袋功能的预期变化。
结果:从回肠袋功能障碍检索中回顾了27项研究,和38来自回肠肛门袋功能。3项研究试图定义正常的眼袋功能,10试图测量小袋功能,和4旨在评分袋功能。只有3篇论文涉及眼袋生理学。
结论:大多数关于囊袋功能和功能障碍的研究没有考虑恢复性直肠结肠切除术后排便生理的预期变化。这意味着大多数对袋功能的研究得出的结论缺乏重要的维度。见研讨会视频。
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