关键词: Lung cancer (oncology) Pneumonia (respiratory medicine)

Mesh : Humans Male Lymphoma, B-Cell, Marginal Zone / diagnosis diagnostic imaging Lung / pathology Pneumonia / pathology Bronchial Neoplasms / pathology Radiography

来  源:   DOI:10.1136/bcr-2023-255075   PDF(Pubmed)

Abstract:
Mucosa-associated lymphoid tissue (MALT) lymphoma is an uncommon extranodal low-grade B-cell lymphoma. Pulmonary MALT lymphomas originate from bronchial MALT and are also referred to as bronchial-associated lymphoid tissue lymphomas. MALT lymphomas of the lung are slow-growing tumours and usually present as asymptomatic chronic alveolar opacities visible on chest radiographs or with non-specific pulmonary symptoms. Here we described a case of a male patient in his early 50s with cough and chest pain for 4 years. His CT chest scan showed consolidation in the lingula and left lower lobe. Histopathology of the specimen obtained from cryobiopsy of the lung lesion showed a dense monomorphic lymphoid infiltrate, and immunohistochemistry confirmed the diagnosis of MALT lymphoma. The prognosis of pulmonary MALT lymphomas is good with >80% 5-year survival rates. This case highlights that MALT lymphoma should be considered as a differential diagnosis while evaluating cases with non-resolving consolidation.
摘要:
粘膜相关淋巴组织(MALT)淋巴瘤是一种罕见的结外低度B细胞淋巴瘤。肺MALT淋巴瘤起源于支气管MALT,也称为支气管相关淋巴组织淋巴瘤。肺MALT淋巴瘤是生长缓慢的肿瘤,通常表现为胸片上可见的无症状慢性肺泡混浊或具有非特异性肺部症状。在这里,我们描述了一个50岁出头的男性患者咳嗽和胸痛4年的病例。他的CT胸部扫描显示舌部和左下叶巩固。从肺部病变的冷冻活检中获得的标本的组织病理学显示出密集的单形淋巴浸润,免疫组织化学证实了MALT淋巴瘤的诊断。肺MALT淋巴瘤的预后良好,5年生存率>80%。该病例强调MALT淋巴瘤应被视为鉴别诊断,同时评估未解决的合并病例。
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