PDF(Pubmed)
Abstract：
UNASSIGNED: Epithelioid hemangioma (EH) is a benign vascular tumor displaying diverse histomorphologies. Among these, one EH subtype comprises cellular sheets of atypical epithelioid cells, posing potential challenges in distinguishing it from malignant vascular lesions. In this case report, we present a cutaneous cellular EH that carries the rare GATA6::FOXO1 gene fusion, a recent discovery. Our aim is to provide an updated insight into the evolving knowledge of EHs while delving into the histologic and molecular characteristics of the primary differential diagnoses.
摘要：
■上皮样血管瘤（EH）是一种良性血管肿瘤，表现出多种组织形态。其中,一种EH亚型包括非典型上皮样细胞的细胞片，在将其与恶性血管病变区分开方面存在潜在挑战。在这个案例报告中,我们提出了一个皮肤细胞EH，携带罕见的GATA6::FOXO1基因融合，最近的发现。我们的目标是提供对EHs不断发展的知识的最新见解，同时深入研究主要鉴别诊断的组织学和分子特征。
