PDF(Pubmed)
Abstract：
UNASSIGNED: Brucellosis is an anthropo-zoonotic infectious disease caused by various Brucella species. It is usually transmitted through contact with infected animals or consumption of contaminated animal products. Brucellosis most commonly affects the musculoskeletal and reticuloendothelial system with additional involvement observed in gastrointestinal system, urinary tract, reproductive system, central nervous system, and cardiovascular system. Skin involvement is extremely rare in brucellosis. Here, we report a rare case of Brucella melitensis infection developing in a back wound following a lumbar disc herniation surgery over 14 years ago.
UNASSIGNED: A 34-year-old male patient, who had a herniated disc surgery 14 years ago, was admitted to the hospital with complaints of joint pain, sweating and discharge at the surgery site. Wound culture revealed the presence of Gram negative cocobacilli which was identified as Brucella melitensis. The subsequent diagnostic tests, including the Rose-Bengal and Brucella Capture test positivity at a titer of 1/320 confirmed the diagnosis. The patient received six weeks of doxycycline (200 mg/day, orally) and rifampin (600 mg/day orally) treatment, accompanied by wound care procedures. Daily cleaning, sterile dressing, and wound debridement were employed. Following treatment, the patient\'s condition improved, and wound discharge ceased. Continuous monitoring showed no signs of relapse, achieving complete remission.
UNASSIGNED: Brucella spp. should be considered as a potential cause of wound infections developing after surgery or trauma in brucellosis-endemic areas. This report also emphasizes the importance of promptly determining the cause of infection before initiating antibiotic treatment.
UNASSIGNED: A 34-year-old male patient, who had a herniated disc surgery 14 years ago, was admitted to the hospital with complaints of joint pain, sweating and discharge at the surgery site. Wound culture revealed the presence of Gram negative cocobacilli which was identified as Brucella melitensis. The subsequent diagnostic tests, including the Rose-Bengal and Brucella Capture test positivity at a titer of 1/320 confirmed the diagnosis. The patient received six weeks of doxycycline (200 mg/day, orally) and rifampin (600 mg/day orally) treatment, accompanied by wound care procedures. Daily cleaning, sterile dressing, and wound debridement were employed. Following treatment, the patient\'s condition improved, and wound discharge ceased. Continuous monitoring showed no signs of relapse, achieving complete remission.
UNASSIGNED: Brucella spp. should be considered as a potential cause of wound infections developing after surgery or trauma in brucellosis-endemic areas. This report also emphasizes the importance of promptly determining the cause of infection before initiating antibiotic treatment.
摘要：
■布鲁氏菌病是由各种布鲁氏菌引起的人类人畜共患病传染病。它通常通过接触受感染的动物或食用受污染的动物产品传播。布鲁氏菌病最常见地影响肌肉骨骼和网状内皮系统，在胃肠道系统中观察到额外的参与，泌尿道,生殖系统,中枢神经系统,和心血管系统。皮肤受累在布鲁氏菌病中极为罕见。这里,我们报道了一例罕见的布鲁氏菌感染病例，在14年前的腰椎间盘突出症手术后，在背部伤口发展。
■一名34岁男性患者,14年前做了椎间盘突出手术，因关节痛入院，在手术部位出汗和出院。伤口培养显示存在革兰氏阴性梭菌，被鉴定为布鲁氏菌。随后的诊断测试，包括玫瑰孟加拉和布鲁氏菌捕获试验阳性，滴度为1/320，证实了诊断。患者接受了6周的强力霉素（200毫克/天，口服）和利福平（口服600毫克/天）治疗，伴随着伤口护理程序。日常清洁,无菌敷料,并进行了伤口清创术。治疗后,病人的病情好转，伤口放电停止了。持续监测显示没有复发迹象,实现完全缓解。
■布鲁氏菌属。应被认为是布鲁氏菌病流行地区手术或创伤后伤口感染的潜在原因。该报告还强调了在开始抗生素治疗之前及时确定感染原因的重要性。
■一名34岁男性患者,14年前做了椎间盘突出手术，因关节痛入院，在手术部位出汗和出院。伤口培养显示存在革兰氏阴性梭菌，被鉴定为布鲁氏菌。随后的诊断测试，包括玫瑰孟加拉和布鲁氏菌捕获试验阳性，滴度为1/320，证实了诊断。患者接受了6周的强力霉素（200毫克/天，口服）和利福平（口服600毫克/天）治疗，伴随着伤口护理程序。日常清洁,无菌敷料,并进行了伤口清创术。治疗后,病人的病情好转，伤口放电停止了。持续监测显示没有复发迹象,实现完全缓解。
■布鲁氏菌属。应被认为是布鲁氏菌病流行地区手术或创伤后伤口感染的潜在原因。该报告还强调了在开始抗生素治疗之前及时确定感染原因的重要性。
