PDF(Pubmed)
Abstract：
Diet is a modifiable risk factor in the prevention and management of obesity, and various foods have the potential to aid in obesity management by modulating different pathways involved in the disease\'s pathology. We performed a systematic review of literature, using CINAHL, PubMed, and Google Scholar, focusing on the antiobesity potential of foods crops and functional food products, and their mechanisms of action and clinical evidence. Sixty-four articles were identified, of which 41 investigated food crops, while 23 investigated functional products. Food crops, such as cereals, vegetables, fruits, mushrooms, seaweeds, legumes, herbs, spices, and cocoa seeds, have antiobesity effects through mechanisms such as altering the metabolism of glucolipids by inhibiting enzymes like α-amylase and α-glucosidase, stimulating the bioenergetics of thermogenic fat, modulating gut microbiota, and inhibiting lipogenesis and storage. In addition, developed functional teas, beverages, and yoghurt have antiobesity effects through similar or different mechanisms, such as enhancing energy expenditure and satiety, suppressing adipogenesis and lipolysis, improving glucose and lipid metabolism, and altering hormonal secretion. This review reemphasized the significance of food in the control of obesity, and highlights the distinct methods these explored foods exert their antiobesity effects. In conclusion, foods are safe and effective means of combating obesity without the side effects of conventional drugs, which can help inform dietary choices, assist professionals in providing more accurate advice, and also lead to better understanding of food and its effect on overall health of the public. This approach will eradicate global diseases, especially if more underutilized and indigenous food crops are extensively researched.
摘要：
饮食是预防和管理肥胖的一个可改变的危险因素，各种食物有可能通过调节与疾病病理有关的不同途径来帮助控制肥胖。我们对文献进行了系统的回顾，使用CINAHL，PubMed,和谷歌学者，专注于粮食作物和功能性食品的抗肥胖潜力，以及它们的作用机制和临床证据。确定了64篇文章，其中41人调查了粮食作物，而23人调查了功能性产品。粮食作物,比如谷物,蔬菜,水果,蘑菇,海藻,豆类,草药,香料,和可可种子，通过抑制α-淀粉酶和α-葡萄糖苷酶等酶改变糖脂代谢等机制具有抗肥胖作用，刺激产热脂肪的生物能量学，调节肠道微生物群，并抑制脂肪生成和储存。此外,开发功能茶，饮料,酸奶通过相似或不同的机制具有抗肥胖作用，例如增加能量消耗和饱腹感，抑制脂肪生成和脂肪分解，改善葡萄糖和脂质代谢，改变荷尔蒙分泌.这篇综述再次强调了食物在控制肥胖中的重要性。并强调了这些探索的食物发挥其抗肥胖作用的独特方法。总之,食品是对抗肥胖的安全有效手段，没有常规药物的副作用，这可以帮助告知饮食选择，协助专业人士提供更准确的建议，并使人们更好地了解食物及其对公众整体健康的影响。这种方法将根除全球疾病，特别是如果更多的未充分利用和本土粮食作物被广泛研究。
