Abstract：
BACKGROUND: Striae are fine lines on the body that occur following rapid skin stretching (i.e., following pregnancy, puberty, weight change). The aim of this systematic review was to assess the current literature on treatment outcomes associated with striae.
OBJECTIVE: (1) To assess the efficacy and safety of different treatment options reported for striae and (2) to determine the most efficient treatment options for each subtype of striae.
METHODS: A systematic search was performed on MEDLINE, Embase, and PubMed with no publication date or language restrictions. All articles with original data and treatment outcomes were included.
RESULTS: One hundred fifty-one studies on the treatment of striae met inclusion criteria (83% female, mean age at diagnosis = 30.2), and 4,806 treatment outcomes of striae were described. Energy-based devices were the most reported modality (56%; n = 2,699/4,806), followed by topicals (19%; n = 919/4,806) and combinations (12%; n = 567/4,806). The highest rates of complete response were injection-based devices for striae distensae (7%; n = 12/172), CO 2 lasers for striae alba (4%; n = 12/341), and platelet-rich plasma injections for striae rubra (31%; n = 4/13).
CONCLUSIONS: Treatment options for striae are varied, likely indicating a lack of effective treatments due to the diversity in striae subtypes. Improved outcomes in striae management may be achieved with additional research on factors that predict treatment response.
OBJECTIVE: (1) To assess the efficacy and safety of different treatment options reported for striae and (2) to determine the most efficient treatment options for each subtype of striae.
METHODS: A systematic search was performed on MEDLINE, Embase, and PubMed with no publication date or language restrictions. All articles with original data and treatment outcomes were included.
RESULTS: One hundred fifty-one studies on the treatment of striae met inclusion criteria (83% female, mean age at diagnosis = 30.2), and 4,806 treatment outcomes of striae were described. Energy-based devices were the most reported modality (56%; n = 2,699/4,806), followed by topicals (19%; n = 919/4,806) and combinations (12%; n = 567/4,806). The highest rates of complete response were injection-based devices for striae distensae (7%; n = 12/172), CO 2 lasers for striae alba (4%; n = 12/341), and platelet-rich plasma injections for striae rubra (31%; n = 4/13).
CONCLUSIONS: Treatment options for striae are varied, likely indicating a lack of effective treatments due to the diversity in striae subtypes. Improved outcomes in striae management may be achieved with additional research on factors that predict treatment response.
摘要：
背景：条纹是皮肤快速拉伸后出现的身体上的细纹（即，怀孕后,青春期,重量变化)。本系统综述的目的是评估与纹相关的治疗结果的现有文献。
目的：（1）评估针对纹状体报告的不同治疗方案的疗效和安全性，以及（2）确定每种纹状体亚型的最有效治疗方案。
方法：对MEDLINE进行了系统搜索，Embase,和PubMed，没有发布日期或语言限制。包括所有具有原始数据和治疗结果的文章。
结果：一百五十一项关于纹治疗的研究符合纳入标准（83％为女性，诊断时的平均年龄=30.2)，并描述了4,806例纹状体的治疗结果。基于能量的设备是报告最多的模态(56%；n=2,699/4,806)，其次是局部药物（19％；n=919/4,806）和组合（12％；n=567/4,806）。完全缓解率最高的是基于注射的横纹装置（7％；n=12/172），用于白纹的CO2激光器（4％；n=12/341），和富含血小板的血浆注射治疗皱纹纹（31％；n=4/13）。
结论：纹的治疗方案多种多样，可能表明由于纹状体亚型的多样性，缺乏有效的治疗方法。通过对预测治疗反应的因素进行额外的研究，可以改善纹管理的结果。
目的：（1）评估针对纹状体报告的不同治疗方案的疗效和安全性，以及（2）确定每种纹状体亚型的最有效治疗方案。
方法：对MEDLINE进行了系统搜索，Embase,和PubMed，没有发布日期或语言限制。包括所有具有原始数据和治疗结果的文章。
结果：一百五十一项关于纹治疗的研究符合纳入标准（83％为女性，诊断时的平均年龄=30.2)，并描述了4,806例纹状体的治疗结果。基于能量的设备是报告最多的模态(56%；n=2,699/4,806)，其次是局部药物（19％；n=919/4,806）和组合（12％；n=567/4,806）。完全缓解率最高的是基于注射的横纹装置（7％；n=12/172），用于白纹的CO2激光器（4％；n=12/341），和富含血小板的血浆注射治疗皱纹纹（31％；n=4/13）。
结论：纹的治疗方案多种多样，可能表明由于纹状体亚型的多样性，缺乏有效的治疗方法。通过对预测治疗反应的因素进行额外的研究，可以改善纹管理的结果。
