UNASSIGNED: A cross-sectional survey was conducted in adult patients with highly suspected TB in two cities of China, spanning from May 9, 2023, to June 30, 2023. We compare the clinical characteristics, nutrition status, fasting blood glucose (FBG) level, living style, and knowledge of TB and DM at admission between patients with and without DM. Univariate and multivariate logistic regression analyses were employed to identify risk factors associated with TB-DM comorbidities.
UNASSIGNED: Of the 322 patients diagnosed with pulmonary tuberculosis (PTB), 54 individuals (16.8%) had comorbid diabetes mellitus (DM). This included 43 males (13.4%) and 11 females (3.4%). The average age was 55.44 ± 12.36 in DM patients and 46.09 ± 16.87 in non-DM patients. A multivariate logistic regression analysis revealed that male (adjusted odds ratio [aOR]=3.29, 95% confidence interval [CI]: 1.05-10.30), age older than 47 years (aOR = 1.04, 95% CI: 1.01-1.07), having a family history of diabetes (aOR = 5.09, 95% CI: 1.28-20.32), and an elevated random blood glucose level (aOR = 1.6, 95% CI: 1.38-1.86) were risk factors for DM in patients with PTB. Furthermore, it was found that diabetes awareness (aOR = 0.07, 95% CI: 0.03-0.21) and zero, light to moderate alcohol consumption were associated with a lower risk of diabetes.
UNASSIGNED: Diabetes is prevalent in patients with active PTB. Screening and raising awareness of DM are recommended, particularly in men after middle age with a family history of diabetes and elevated random blood glucose. Early diagnosis of diabetes and effective diabetes prevention may reduce the dual burden of TB-DM comorbidity.
■在中国两个城市对高度怀疑的成人结核病患者进行了横断面调查,从2023年5月9日到2023年6月30日。我们比较了临床特征,营养状况,空腹血糖(FBG)水平,生活方式,以及有和无DM患者入院时对TB和DM的了解。采用单变量和多变量逻辑回归分析来确定与TB-DM合并症相关的危险因素。
■在诊断为肺结核(PTB)的322例患者中,54例(16.8%)患有糖尿病(DM)。其中包括43名男性(13.4%)和11名女性(3.4%)。DM患者平均年龄为55.44±12.36,非DM患者平均年龄为46.09±16.87。多变量逻辑回归分析显示,男性(调整后比值比[aOR]=3.29,95%置信区间[CI]:1.05-10.30),年龄大于47岁(aOR=1.04,95%CI:1.01-1.07),有糖尿病家族史(aOR=5.09,95%CI:1.28-20.32),随机血糖水平升高(aOR=1.6,95%CI:1.38-1.86)是PTB患者DM的危险因素。此外,发现糖尿病意识(aOR=0.07,95%CI:0.03-0.21)和零,轻度至中度饮酒与糖尿病风险较低相关.
■糖尿病在活动性PTB患者中普遍存在。建议筛查和提高对DM的认识,尤其是中年以后有糖尿病家族史和随机血糖升高的男性。糖尿病的早期诊断和有效的糖尿病预防可以减轻TB-DM共病的双重负担。