PDF(Pubmed)
Abstract：
BACKGROUND: Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities include surgical resection, chemotherapy, or a combination of both.
METHODS: Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery.
CONCLUSIONS: Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment.
METHODS: Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery.
CONCLUSIONS: Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment.
摘要：
背景：胃脾瘘是各种疾病的罕见且可能致命的并发症。淋巴瘤是最常见的原因。它可以自发或化疗后发生。由于存在进入肿块的空气，胃脾瘘的诊断可能与脾脓肿混淆。瘘管的计算机断层扫描识别是正确诊断的关键。治疗方式包括手术切除，化疗,或两者的组合。
方法：这里我们报告2例弥漫性大B细胞淋巴瘤引起的胃脾瘘。第一位患者是一名54岁的白人妇女，患有巨大的原发性脾弥漫性大B细胞淋巴瘤，导致胃中自发性瘘管的发展。第二名患者是一名48岁的白人男性患者，患有巨大的脾弥漫性大B细胞淋巴瘤，并在化疗后并发瘘管。两名患者均在手术后几天死于感染性休克。
结论：胃脾瘘是一种罕见的并发症，预后不良，手术是目前首选的治疗方法。
方法：这里我们报告2例弥漫性大B细胞淋巴瘤引起的胃脾瘘。第一位患者是一名54岁的白人妇女，患有巨大的原发性脾弥漫性大B细胞淋巴瘤，导致胃中自发性瘘管的发展。第二名患者是一名48岁的白人男性患者，患有巨大的脾弥漫性大B细胞淋巴瘤，并在化疗后并发瘘管。两名患者均在手术后几天死于感染性休克。
结论：胃脾瘘是一种罕见的并发症，预后不良，手术是目前首选的治疗方法。
