甘油磷酸二酯抑制巴顿病中的溶酶体磷脂分解代谢。
关键词: Batten disease CLN3 GPDs PLA2G15 PLBD2 glycerophosphodiesters lysosomal storage disease lysosome neurodegeneration phospholipase phospholipid metabolism
Mesh : Mice Animals Child Humans Membrane Glycoproteins / metabolism Molecular Chaperones / metabolism Neuronal Ceroid-Lipofuscinoses / genetics metabolism pathology Lysosomes / metabolism Phospholipases / metabolism Glycerophospholipids / metabolism Phospholipids / metabolism
来 源:
DOI:10.1016/j.molcel.2024.02.006
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