Abstract:
Stretchable sweat sensors are promising technology that can acquire biomolecular insights for health and fitness monitoring by intimate integration with the body. However, current sensors often require microfabricated microfluidic channels to control sweat flow during lab-on-body analysis, which makes effective and affordable sweat sampling a significant practical challenge. Here, we present stretchable and sweat-wicking patches that utilize bioinspired smart wettable membranes for the on-demand manipulation of sweat flow. In a scalable process, the membrane is created by stacking hydrophobic elastomer nanofibers onto soft microfoams with predefined two-dimensional superhydrophobic and superhydrophilic patterns. The engineered heterogeneous wettability distribution allows these porous membranes to achieve enhanced extraction and selective collection of sweat in embedded assays. Despite the simplified architecture, the color reactions between sweat and chemical indicators are inhibited from directly contacting the skin to achieve a largely improved operation safety. The sensing patches can simultaneously quantify pH, urea, and calcium in sweat through digital colorimetric analysis with smartphone images. The construction with all compliant materials renders these patches soft and stretchy to achieve conformal attachment to the skin. Successfully analyzing sweat compositions after physical exercises illustrates the practical suitability of these skin-attachable sensors for health tracking and point-of-care diagnosis.
摘要:
可拉伸的汗液传感器是有前途的技术,可以通过与身体的紧密整合来获得生物分子的见解,用于健康和健身监测。然而,电流传感器通常需要微制造的微流体通道来控制身体实验室分析过程中的汗液流动,这使得有效和负担得起的汗液采样成为一个重大的实际挑战。这里,我们提出了可拉伸和吸汗的贴片,利用生物启发的智能可湿性膜按需操作的汗液流动。在可扩展的过程中,通过将疏水性弹性体纳米纤维堆叠到具有预定义的二维超疏水和超亲水图案的软微泡沫上而产生膜。工程化的异质润湿性分布允许这些多孔膜在嵌入式测定中实现汗液的增强提取和选择性收集。尽管简化了架构,汗液和化学指示剂之间的颜色反应被抑制而不直接接触皮肤,从而大大提高了操作安全性。传感贴片可以同时量化pH值,尿素,通过智能手机图像的数字比色分析和汗液中的钙。具有所有顺应性材料的构造使得这些贴片柔软且有弹性,以实现与皮肤的保形附接。在体育锻炼后成功地分析汗液成分说明了这些皮肤可附着传感器用于健康跟踪和护理点诊断的实际适用性。