PDF(Pubmed)
Abstract：
UNASSIGNED: Anemia after surgery is common and is associated with adverse clinical outcomes. Understanding the incidence and risk factors for postoperative anemia is important to reduce anemia-related complications and blood transfusion. There is lack of data regarding postoperative anemia and its contributing factors in neurosurgery. This study evaluates the incidence and risk factors of postoperative anemia, and its impact on clinical outcomes.
UNASSIGNED: This was a single centre, retrospective study of patients who underwent elective neurosurgery over seven months. Data regarding age, gender, body mass index, American Society of Anesthesiologists (ASA) physical status, diagnosis, surgery, preoperative hemoglobin, surgery duration, intraoperative blood loss and red blood cell (RBC) transfusion, dose of tranexamic acid, intraoperative fluid balance, years of surgeon\'s experience, postoperative hemoglobin, postoperative RBC transfusion, Glasgow Coma Scale (GCS) score at hospital discharge, and duration of postoperative intensive care unit and hospital stay were collected. Logistic regression was used to identify predictors of postoperative anemia.
UNASSIGNED: The incidence of postoperative anemia was 11.3% (116/1025). On univariate analysis; age, preoperative hemoglobin, surgery duration, gender, ASA grade, surgery type, and surgeon\'s experience were associated with postoperative anemia. Lower preoperative hemoglobin (p<0.001) and non-tumor surgery (p<0.001) were predictive of postoperative anemia on multivariate analysis. Postoperative anemia resulted in increased RBC transfusion (p<0.001) and lower GCS score at discharge (p=0.012).
UNASSIGNED: Atleast one in ten patients undergoing elective neurosurgery develop postoperative anemia. Lower preoperative hemoglobin and non-tumor surgery predict anemia. Anemia results in increased RBC transfusion and lower discharge GCS score.
UNASSIGNED: This was a single centre, retrospective study of patients who underwent elective neurosurgery over seven months. Data regarding age, gender, body mass index, American Society of Anesthesiologists (ASA) physical status, diagnosis, surgery, preoperative hemoglobin, surgery duration, intraoperative blood loss and red blood cell (RBC) transfusion, dose of tranexamic acid, intraoperative fluid balance, years of surgeon\'s experience, postoperative hemoglobin, postoperative RBC transfusion, Glasgow Coma Scale (GCS) score at hospital discharge, and duration of postoperative intensive care unit and hospital stay were collected. Logistic regression was used to identify predictors of postoperative anemia.
UNASSIGNED: The incidence of postoperative anemia was 11.3% (116/1025). On univariate analysis; age, preoperative hemoglobin, surgery duration, gender, ASA grade, surgery type, and surgeon\'s experience were associated with postoperative anemia. Lower preoperative hemoglobin (p<0.001) and non-tumor surgery (p<0.001) were predictive of postoperative anemia on multivariate analysis. Postoperative anemia resulted in increased RBC transfusion (p<0.001) and lower GCS score at discharge (p=0.012).
UNASSIGNED: Atleast one in ten patients undergoing elective neurosurgery develop postoperative anemia. Lower preoperative hemoglobin and non-tumor surgery predict anemia. Anemia results in increased RBC transfusion and lower discharge GCS score.
摘要：
■手术后贫血很常见，并与不良临床结局相关。了解术后贫血的发生率和危险因素对减少贫血相关并发症和输血有重要意义。缺乏有关神经外科术后贫血及其影响因素的数据。这项研究评估了术后贫血的发生率和危险因素，及其对临床结果的影响。
■这是一个单一的中心，对接受择期神经外科手术超过7个月的患者进行回顾性研究。关于年龄的数据，性别,身体质量指数,美国麻醉医师协会（ASA）的身体状况，诊断,手术,术前血红蛋白,手术持续时间,术中失血和红细胞（RBC）输血，氨甲环酸的剂量，术中液体平衡,多年的外科医生经验，术后血红蛋白,术后红细胞输注,出院时格拉斯哥昏迷量表（GCS）评分，收集术后重症监护病房的持续时间和住院时间。采用Logistic回归分析确定术后贫血的预测因子。
■术后贫血发生率为11.3%(116/1025)。关于单变量分析；年龄，术前血红蛋白,手术持续时间,性别,ASA等级,手术类型,和外科医生的经验与术后贫血有关。根据多变量分析，术前血红蛋白较低（p<0.001）和非肿瘤手术（p<0.001）是术后贫血的预测因素。术后贫血导致出院时红细胞输血增加（p<0.001）和GCS评分降低（p=0.012）。
■接受择期神经外科手术的患者中至少有十分之一出现术后贫血。术前血红蛋白降低和非肿瘤手术预测贫血。贫血导致红细胞输血增加和出院GCS评分降低。
■这是一个单一的中心，对接受择期神经外科手术超过7个月的患者进行回顾性研究。关于年龄的数据，性别,身体质量指数,美国麻醉医师协会（ASA）的身体状况，诊断,手术,术前血红蛋白,手术持续时间,术中失血和红细胞（RBC）输血，氨甲环酸的剂量，术中液体平衡,多年的外科医生经验，术后血红蛋白,术后红细胞输注,出院时格拉斯哥昏迷量表（GCS）评分，收集术后重症监护病房的持续时间和住院时间。采用Logistic回归分析确定术后贫血的预测因子。
■术后贫血发生率为11.3%(116/1025)。关于单变量分析；年龄，术前血红蛋白,手术持续时间,性别,ASA等级,手术类型,和外科医生的经验与术后贫血有关。根据多变量分析，术前血红蛋白较低（p<0.001）和非肿瘤手术（p<0.001）是术后贫血的预测因素。术后贫血导致出院时红细胞输血增加（p<0.001）和GCS评分降低（p=0.012）。
■接受择期神经外科手术的患者中至少有十分之一出现术后贫血。术前血红蛋白降低和非肿瘤手术预测贫血。贫血导致红细胞输血增加和出院GCS评分降低。
