Is there any association between celiac disease, myelodysplastic symdrome and primary sclerosing cholangitis?: A rare case report.

乳糜泻之间有什么关联吗 ，骨髓增生异常综合征和原发性硬化性胆管炎 ？ ： 罕见病例报告。

• 发表时间: 2024 Mar
• 来源期刊: JGH Open
• DOI: 10.1002/jgh3.13043
• PMID: 38444633
• 文章类型: Case Reports
• 作者列表: Hamsho S,Hariri MA,Sleiay B,Alhussen AHD,Sleiay M

关键词: celiac disease; myelodysplastic syndrome; primary sclerosing cholangitis; ultrasound

Abstract

Celiac disease (CD) is an autoimmune disease characterized by a specific serological and histological profile. Hematological findings are one of the most common presentations and can sometimes be the only manifestation of the disease. In patients with unexplained isolated hematological abnormalities, a high index of suspicion for CD is necessary. A 33-year-old woman was admitted to the Department of Gastroenterology and Hepatology because of abdominal pain and fatigue. She was diagnosed with myelodysplastic syndrome. After many investigations, it is explained that she has CD. It is important to consider myelodysplastic syndrome as a hematological manifestation of CD. All patients with myelodysplasia should be investigated for CD and related conditions such as primary sclerosing cholangitis.

摘要

乳糜泻（CD）是一种自身免疫性疾病，其特征在于具有特定的血清学和组织学特征。血液学发现是最常见的表现之一，有时可能是该疾病的唯一表现。在无法解释的孤立性血液学异常的患者中，对CD的高度怀疑是必要的。一名33岁的妇女因腹痛和疲劳而进入胃肠病和肝病科。她被诊断患有骨髓增生异常综合征。经过多次调查,据说她有CD。重要的是将骨髓增生异常综合征视为CD的血液学表现。所有患有骨髓增生异常的患者都应进行CD和相关疾病的调查，例如原发性硬化性胆管炎。