PDF(Pubmed)
Abstract：
BACKGROUND: Transcranial color-coded duplex ultrasonography (TCCD) is an important diagnostic tool in the investigation of cerebrovascular diseases. TCCD is often hampered by the temporal window that ultrasound cannot penetrate. Rapidly determine whether ultrasound can penetrate the temporal window in order to determine whether to use other acoustic windows to complete the examination process. In this study, Skull thickness can be measured simultaneously during TCCD examination, which makes it possible to use skull thickness to rapidly determine whether the temporal window is penetrated by ultrasound.
METHODS: This retrospective study included 301 patients with clinical symptoms of cerebrovascular diseases. These 301 patients were divided into an impenetrable temporal window (ITW) group and a penetrable temporal window group according to the results of the TCCD examination.
RESULTS: The area under the receiver operating characteristic (ROC) curve (AUC) for skull thickness was 0.887 (cutoff value 1.045 cm). Following multivariate logistic regression, sex, age, and skull thickness were used to develop a nomogram. The AUC for the nomogram was 0.923 (cutoff value 0.407).
CONCLUSIONS: The skull thickness at the temporal window was measured by ultrasound, which was convenient and accurate. The probability of ITW in females was higher than that in males, and it increased with age. In this study, a prediction model incorporating sex, age and skull thickness could predict ITW probability well. If the patient\'s temporal window was rapidly predicted as an ITW, other acoustic window examinations were used to complete the TCCD examination process to optimize the TCCD examination process of cerebrovascular diseases and facilitate the popularization of TCCD in clinical application.
METHODS: This retrospective study included 301 patients with clinical symptoms of cerebrovascular diseases. These 301 patients were divided into an impenetrable temporal window (ITW) group and a penetrable temporal window group according to the results of the TCCD examination.
RESULTS: The area under the receiver operating characteristic (ROC) curve (AUC) for skull thickness was 0.887 (cutoff value 1.045 cm). Following multivariate logistic regression, sex, age, and skull thickness were used to develop a nomogram. The AUC for the nomogram was 0.923 (cutoff value 0.407).
CONCLUSIONS: The skull thickness at the temporal window was measured by ultrasound, which was convenient and accurate. The probability of ITW in females was higher than that in males, and it increased with age. In this study, a prediction model incorporating sex, age and skull thickness could predict ITW probability well. If the patient\'s temporal window was rapidly predicted as an ITW, other acoustic window examinations were used to complete the TCCD examination process to optimize the TCCD examination process of cerebrovascular diseases and facilitate the popularization of TCCD in clinical application.
摘要：
背景：经颅彩色编码双工超声检查（TCCD）是脑血管疾病研究中的重要诊断工具。TCCD通常受到超声无法穿透的时间窗口的阻碍。快速确定超声是否可以穿透时间窗口,以便确定是否使用其他声学窗口来完成检查过程。在这项研究中,TCCD检查时可同时测量颅骨厚度,这使得可以使用颅骨厚度来快速确定超声是否穿透了时间窗口。
方法：这项回顾性研究包括301例有脑血管疾病临床症状的患者。根据TCCD检查结果，将这301例患者分为不可穿透时间窗（ITW）组和可穿透时间窗组。
结果：颅骨厚度的接收器工作特征（ROC）曲线（AUC）下面积为0.887（截止值1.045cm）。在多变量逻辑回归后，性别,年龄,和颅骨厚度被用来绘制列线图。列线图的AUC为0.923(截止值0.407)。
结论：通过超声测量颞窗的颅骨厚度，这是方便和准确的。女性发生ITW的概率高于男性，随着年龄的增长。在这项研究中,结合性别的预测模型，年龄和颅骨厚度可以很好地预测ITW概率。如果患者的时间窗口被快速预测为ITW，通过其他声窗检查完成TCCD检查流程，优化TCCD检查流程，促进TCCD在临床应用中的推广。
方法：这项回顾性研究包括301例有脑血管疾病临床症状的患者。根据TCCD检查结果，将这301例患者分为不可穿透时间窗（ITW）组和可穿透时间窗组。
结果：颅骨厚度的接收器工作特征（ROC）曲线（AUC）下面积为0.887（截止值1.045cm）。在多变量逻辑回归后，性别,年龄,和颅骨厚度被用来绘制列线图。列线图的AUC为0.923(截止值0.407)。
结论：通过超声测量颞窗的颅骨厚度，这是方便和准确的。女性发生ITW的概率高于男性，随着年龄的增长。在这项研究中,结合性别的预测模型，年龄和颅骨厚度可以很好地预测ITW概率。如果患者的时间窗口被快速预测为ITW，通过其他声窗检查完成TCCD检查流程，优化TCCD检查流程，促进TCCD在临床应用中的推广。
