关键词: COVID-19 Computed tomography Radiation cancer risk

Mesh : Female Male Humans Adult Middle Aged Aged Cross-Sectional Studies COVID-19 Testing Neoplasms, Radiation-Induced / diagnosis epidemiology etiology COVID-19 / epidemiology Tomography, X-Ray Computed / adverse effects Radiation, Ionizing

来  源:   DOI:10.1186/s12885-024-12050-x   PDF(Pubmed)

Abstract:
BACKGROUND: The surge in the utilization of CT scans for COVID-19 diagnosis and monitoring during the pandemic is undeniable. This increase has brought to the forefront concerns about the potential long-term health consequences, especially radiation-induced cancer risk. This study aimed to quantify the potential cancer risk associated with CT scans performed for COVID-19 detection.
METHODS: In this cross-sectional study data from a total of 561 patients, who were referred to the radiology center at Imam Hossein Hospital in Shahroud, was collected. CT scan reports were categorized into three groups based on the radiologist\'s interpretation. The BEIR VII model was employed to estimate the risk of radiation-induced cancer.
RESULTS: Among the 561 patients, 299 (53.3%) were males and the average age of the patients was 49.61 ± 18.73 years. Of the CT scans, 408 (72.7%) were reported as normal. The average age of patients with normal, abnormal, and potentially abnormal CT scans was 47.57 ± 19.06, 54.80 ± 16.70, and 58.14 ± 16.60 years, respectively (p-value < 0.001). The average effective dose was 1.89 ± 0.21 mSv, with 1.76 ± 0.11 mSv for males and 2.05 ± 0.29 mSv for females (p-value < 0.001). The average risk of lung cancer was 3.84 ± 1.19 and 9.73 ± 3.27 cases per 100,000 patients for males and females, respectively. The average LAR for all cancer types was 10.30 ± 6.03 cases per 100,000 patients.
CONCLUSIONS: This study highlights the critical issue of increased CT scan usage for COVID-19 diagnosis and the potential long-term consequences, especially the risk of cancer incidence. Healthcare policies should be prepared to address this potential rise in cancer incidence and the utilization of CT scans should be restricted to cases where laboratory tests are not readily available or when clinical symptoms are severe.
摘要:
背景:大流行期间CT扫描在COVID-19诊断和监测中的应用激增是不可否认的。这一增长引起了人们对潜在长期健康后果的关注,尤其是辐射引起的癌症风险。这项研究旨在量化与CT扫描检测COVID-19相关的潜在癌症风险。
方法:在这项来自561名患者的横断面研究数据中,他们被转介到沙鲁德伊玛目侯赛因医院的放射学中心,被收集。根据放射科医生的解释,CT扫描报告分为三组。采用BEIRVII模型来估计辐射诱导的癌症的风险。
结果:在561名患者中,男性为299名(53.3%),患者平均年龄为49.61±18.73岁。在CT扫描中,408(72.7%)报告为正常。患者的平均年龄正常,异常,潜在异常CT扫描为47.57±19.06,54.80±16.70,58.14±16.60年,分别(p值<0.001)。平均有效剂量为1.89±0.21mSv,男性为1.76±0.11mSv,女性为2.05±0.29mSv(p值<0.001)。男性和女性患肺癌的平均风险为3.84±1.19和9.73±3.27/10万患者,分别。所有癌症类型的平均LAR为每100,000名患者10.30±6.03例。
结论:这项研究强调了增加CT扫描对COVID-19诊断的关键问题以及潜在的长期后果,尤其是癌症发病的风险。应制定医疗保健政策以应对癌症发病率的这种潜在上升,并且CT扫描的使用应仅限于实验室检查不容易获得或临床症状严重的情况。
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