关键词: Anticancer Combination therapies. Epigenetic pathways Ginsenoside Rg3 Important cellular functions Important pathways

Mesh : Ginsenosides / chemistry pharmacology Humans Neoplasms / drug therapy Antineoplastic Agents, Phytogenic / pharmacology chemistry Medicine, Chinese Traditional Antineoplastic Agents / pharmacology chemistry Cell Proliferation / drug effects Animals

来  源:   DOI:10.2174/0115680266283661240226052054

Abstract:
BACKGROUND: Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.
OBJECTIVE: This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.
摘要:
背景:中医(TCM)具有治疗各种疾病的悠久历史,并且越来越被认为是癌症的补充疗法。从中草药人参中提取的一种有前途的天然化合物是人参皂苷Rg3,其具有显着的抗癌作用。它已在各种癌症和肿瘤中进行了测试,并已被证明可有效抑制癌症。
目的:这项工作涵盖了人参皂苷Rg3在癌症治疗中的作用的各个方面,包括它的生物学功能,关键途径,表观遗传学,以及联合疗法的潜力,所有这些都经过了广泛的研究和阐明。本研究旨在为今后人参皂苷Rg3作为抗癌药物的研究提供参考,为人参皂苷Rg3在肿瘤治疗中的潜在应用提供支持。
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