关键词: China Mycoplasma pneumoniae pneumonia children red cell distribution width retrospective severity

Mesh : Child Humans Mycoplasma pneumoniae Retrospective Studies Risk Factors Erythrocyte Indices Prognosis Erythrocytes Pneumonia / diagnosis

来  源:   DOI:10.2217/bmm-2023-0671

Abstract:
Background: This study aimed to investigate the clinical value of the red blood cell distribution width (RDW) in severe Mycoplasma pneumoniae pneumonia (MPP). Methods: A total of 185 children with diagnosed severe MPP were included. The patients\' case records and laboratory examination data were analyzed retrospectively. The children were grouped into quartiles based on RDW. Results: Univariate analysis revealed that RDW was significantly correlated with the Pediatric Risk of Mortality (PRISM) III score, Sepsis-Related Organ Failure Assessment score, incidence of invasive intubation and 30-day in-hospital mortality. After adjustment for the severity of illness, multivariate analysis revealed that the PRISM III score and RDW were factors independently associated with 30-day in-hospital mortality. Conclusion: This study revealed that RDW could be correlated with the long-term prognosis and severity of severe MPP.
摘要:
背景:本研究旨在探讨红细胞分布宽度(RDW)在重症肺炎支原体肺炎(MPP)中的临床价值。方法:共纳入185例确诊为重症MPP的患儿。回顾性分析患者的病例记录和实验室检查资料。根据RDW将儿童分为四分位数。结果:单因素分析显示,RDW与儿科死亡风险(PRISM)III评分显著相关,脓毒症相关器官衰竭评估评分,侵入性插管的发生率和30天住院死亡率。在调整疾病的严重程度后,多因素分析显示PRISMIII评分和RDW是30天住院死亡率的独立相关因素。结论:本研究表明,RDW可能与严重MPP的长期预后和严重程度有关。
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