关键词: Dyspnea Polypoid mass Seromucinous Hamartoma Sinonasal

来  源:   DOI:10.1007/s12070-023-04276-1   PDF(Pubmed)

Abstract:
UNASSIGNED: Sinonasal hamartomas, according to the 5th edition of the World Health Organisation classification of head and neck tumours are divided into respiratory epithelial adenomatoid hamartoma (REAH), seromucinous hamartoma and chondromesenchymal hamartoma. Seromucinous hamartoma are benign proliferations of small eosinophilic glands surrounded by fibrous stroma and cuboidal cells. Hamartomas of the nasal cavity and paranasal sinuses are rare entities, clinically presenting as sinonasal polyposis.
UNASSIGNED: A 79- year-old female patient was referred to our emergency room due to severe dyspnea. Anterior rhinoscopy revealed unilateral greyish polypoid mass obstructing the middle, inferior and common nasal meatus. Systemic corticosteroids and oxygen therapy were administered under observation. Computerized tomographic imaging of the paranasal sinuses with contrast on all three planes showed an opacified polypoid mass in all meatus and the maxillary, anterior ethmoidal and sphenoidal sinus posteriorly extending to the choanae. On the coronal plane a widening of the olfactory clefts about 12 mm was described. FESS visualized that the polypoid mass originated from the posterior septum and extended to all meatus anteriorly and to the choanae posteriorly. The polypoid lesion was endoscopically completely excised. Histopathological analysis revealed a seromucinous hamartoma.
UNASSIGNED: Seromucinous hamartoma are rare benign tumors of the sinonasal region with potential of malignant alteration. Unfortunately, they share symptoms and clinical appearance with other benign conditions of the sinonasal region. Therefore, it is even more important to consider them as a differential diagnose.
摘要:
鼻窦错构瘤,根据世界卫生组织第5版的头颈部肿瘤分类分为呼吸道上皮腺瘤样错构瘤(REAH),浆膜粘质错构瘤和软骨间充质错构瘤。浆膜粘质错构瘤是由纤维基质和立方细胞包围的小嗜酸性腺体的良性增殖。鼻腔和鼻旁窦错构瘤是罕见的实体,临床表现为鼻窦息肉。
一名79岁女性患者因严重呼吸困难被转诊至急诊室。前鼻镜检查显示单侧灰色息肉样肿块阻塞中部,下鼻道和普通鼻道。观察全身皮质类固醇和氧疗。鼻旁窦的计算机断层扫描成像在所有三个平面上都进行了对比,显示所有鼻道和上颌都有混浊的息肉样肿块,筛前和蝶窦向后延伸至choanae。在冠状平面上,描述了嗅裂的加宽约12毫米。FESS观察到息肉样肿块起源于后隔膜,并向前延伸到所有鼻道,向后延伸到choanae。息肉样病变经内镜完全切除。组织病理学分析显示为浆膜粘质错构瘤。
浆膜黏液性错构瘤是一种罕见的具有潜在恶性改变的鼻腔鼻窦区良性肿瘤。不幸的是,它们与鼻窦区域的其他良性疾病具有共同的症状和临床表现。因此,将它们视为鉴别诊断更为重要。
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