PDF(Pubmed)
Abstract：
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign, reactive vaso-proliferative condition in the dermal and subcutaneous tissues of the head and neck. A 28-year-old female presented with slow-growing painless swelling behind her left ear. FNAC revealed benign soft tissue neoplasm and histopathological examination after surgical excision revealed angiolymphoid hyperplasia with eosinophilia. ALHE origin has been variously attributed to prior trauma, hyperestrogenemia, infectious agents, atopy, reactive hyperplasia, and benign neoplasia. Retroauricular ALHE has been rarely reported. However, on the basis of our case report, it should be a viable differential diagnosis when large subcutaneous tumors of the head and neck are encountered. When big subcutaneous tumors of the head and neck are present, especially in females, a valid differential diagnosis for angiolymphoid hyperplasia with eosinophilia, a rare condition marked by dermal or subcutaneous endothelial cell proliferation, should also be considered.
摘要：
血管淋巴样增生伴嗜酸性粒细胞增多(ALHE)是一种罕见的,良性,头颈部真皮和皮下组织中的反应性血管增生状况。一名28岁的女性左耳后出现缓慢增长的无痛肿胀。FNAC显示良性软组织肿瘤，手术切除后的组织病理学检查显示血管淋巴样增生伴嗜酸性粒细胞增多。ALHE的起源被不同地归因于先前的创伤，高雌激素血症,传染剂,atopy,反应性增生,和良性肿瘤。耳后ALHE很少报道。然而,根据我们的病例报告,当遇到头颈部大的皮下肿瘤时，应该是可行的鉴别诊断。当头颈部有大的皮下肿瘤时，尤其是女性，血管淋巴样增生伴嗜酸性粒细胞增多的有效鉴别诊断，以真皮或皮下内皮细胞增殖为特征的罕见病症，也应该考虑。
