PDF(Pubmed)
Abstract：
Grover\'s disease, also known as transient acantholytic dermatosis (TAD), currently has no published randomized control trials regarding the treatment of the disease; thus, evidence for treatment is largely derived from case studies and case reports. In this case series, we summarize the current treatment options for Grover\'s disease and discuss two cases of refractory Grover\'s disease treated with low-dose oral isotretinoin in patients who previously failed to reach clearance with multiple treatment options. Our aim is to highlight the efficacy of low-dose systemic retinoid therapy in Grover\'s disease when other treatment options prove unsatisfactory.
摘要：
格罗弗的病,也称为短暂性棘层松解性皮肤病（TAD），目前尚无关于该疾病治疗的随机对照试验；因此，治疗证据主要来自案例研究和病例报告。在这个系列中,我们总结了Grover病目前的治疗方案,并讨论了2例难治性Grover病患者接受低剂量口服异维A酸治疗,这些患者以前接受多种治疗方案均未能达到清除。我们的目的是强调低剂量全身类维生素A疗法在格罗弗病中的疗效，当其他治疗方案不令人满意时。
