PDF(Pubmed)
Abstract：
Spindle epithelial tumor with thymic like elements (SETTLE) is a biphasic tumor composed of epithelial and spindle cell components. It is an uncommon indolent tumor arising in the thyroid gland and most commonly affects the children and young adults. This entity is mostly overlooked because of its rarity and diagnostic difficulty on morphology. We discuss two cases of SETTLE with varied presentation, diagnostic challenges and lessons learnt from them.SETTLE should be considered as a differential especially when dealing with a thyroid lesion in young and adolescent. The article discusses the histologic details and common mimickers to be borne in mind aiding in arrival at the final diagnosis on biopsy specimens.
摘要：
具有胸腺样元素的梭形上皮肿瘤（SETTLE）是由上皮和梭形细胞成分组成的双相肿瘤。它是一种罕见的惰性肿瘤，出现在甲状腺，最常见的影响儿童和年轻人。由于其稀有和形态学诊断困难，该实体大多被忽视。我们讨论了两种不同表述的SETTLE案例，诊断挑战和从中吸取的教训。应将SETTLE视为差异，尤其是在处理青年和青少年的甲状腺病变时。本文讨论了组织学细节和要记住的常见模拟物，以帮助到达活检标本的最终诊断。
