Abstract：
Adenovirus pneumonia is a prevalent form of community-acquired pneumonia among children. Research on the epidemiology and economic burden of this disease is crucial for public health, yet comprehensive data remains scarce, making it crucial to highlight on this topic. In this study, the data were extracted from the face sheet of discharge medical records collected from 26 tertiary children\'s hospitals from January 2016 to December 2021. In total, 1854 children with laboratory-confirmed adenovirus pneumonia were hospitalized, accounting for 0.13% of the total number of hospitalized for pneumonia in the database during the period. In addition, this figure represents a meager 0.027% when compared to the total number of hospitalized children. The male-to-female ratio was 1.78:1. The 1-3-year age group had the highest number of inpatients for adenoviral pneumonia and the largest proportion of the total hospitalizations in the same age group. Overall, winter is the primary season for the prevalence of adenovirus pneumonia, however, in southern China, there are two peak seasons, winter and summer. Although patients with 3/4 adenovirus pneumonia had no significant complications, some patients had complications such as respiratory failure, diarrhea, and myocardial damage. The median length of stay of adenovirus pneumonia was 8 d [interquartile range (IQR) 6-11], and the median hospitalization cost was 1293.83 United States dollars (IQR 811.81-2472.51). These valuable epidemiological insights into adenovirus pneumonia in Chinese children can help direct the development of targeted prevention and control strategies and surveillance measures for HAdV infections in this demographic.
摘要：
腺病毒肺炎是儿童社区获得性肺炎的一种流行形式。对这种疾病的流行病学和经济负担的研究对公共卫生至关重要，然而全面的数据仍然很少，强调这个话题至关重要。在这项研究中,这些数据摘自2016年1月至2021年12月26家三级儿童医院的出院医疗记录。总的来说,1854例实验室确诊的腺病毒肺炎患儿住院，占该期间数据库中肺炎住院总数的0.13%。此外,与住院儿童总数相比，这一数字仅为0.027%。男女比例为1.78:1。1-3岁年龄组的腺病毒肺炎住院患者最多，在同一年龄组中占总住院人数的比例最大。总的来说,冬季是腺病毒肺炎流行的主要季节，然而,在中国南方,有两个旺季，冬天和夏天。虽然3/4腺病毒肺炎患者无明显并发症,一些患者出现了呼吸衰竭等并发症，腹泻,和心肌损伤。腺病毒肺炎的中位住院时间为8d[四分位距（IQR）6-11]，中位住院费用为1293.83美元(IQR811.81-2472.51).这些对中国儿童腺病毒肺炎的有价值的流行病学见解可以帮助指导该人群中针对HAdV感染的有针对性的预防和控制策略以及监测措施的制定。
