PDF(Pubmed)
Abstract：
This study explores the complex interplay between coccidioidomycosis (valley fever) and sarcoidosis through a detailed case study of a 54-year-old male patient. The patient presented with elevated calcium levels, chronic kidney disease (CKD), and unintended weight loss. Interdisciplinary collaboration between nephrologists and pulmonologists played a crucial role in navigating the intricate medical challenges, including hypercalcemia, renal dysfunction, and pulmonary anomalies. The diagnostic journey involved extensive laboratory findings uncovering the involvement of both infectious agents and granulomatous disorders. The patient exhibited positive cocci IgG antibodies, indicating coccidioidomycosis. Further complications included glomerulonephritis, as revealed by ongoing systemic inflammation. Tailored management strategies were implemented, including corticosteroid therapy for sarcoidosis-related inflammation and antifungal interventions for coccidioidomycosis. Vigilant monitoring of renal function, hypercalcemia, and weight loss was essential for comprehensive patient care. The study underscores the significance of interdisciplinary collaboration, systematic diagnostics, and personalized patient care in managing complex medical presentations and contributes to understanding the interplay between these two conditions.
摘要：
本研究通过对一名54岁男性患者的详细案例研究，探讨了球孢子菌病（谷热）与结节病之间的复杂相互作用。患者出现钙水平升高，慢性肾脏病（CKD），和意外的减肥。肾病学家和肺科医师之间的跨学科合作在应对复杂的医学挑战方面发挥了至关重要的作用。包括高钙血症,肾功能不全,和肺部异常.诊断过程涉及广泛的实验室发现，揭示了感染原和肉芽肿性疾病的参与。患者表现出阳性球菌IgG抗体，提示球虫菌病.进一步的并发症包括肾小球肾炎，正如正在进行的全身性炎症所揭示的。实施了量身定制的管理策略，包括结节病相关炎症的皮质类固醇治疗和球孢子菌病的抗真菌干预。警惕监测肾功能，高钙血症,减重对于全面的患者护理至关重要.这项研究强调了跨学科合作的重要性，系统诊断，和个性化的病人护理在管理复杂的医疗演示，并有助于理解这两个条件之间的相互作用。
