PDF(Pubmed)
Abstract：
The Epstein-Barr virus (EBV) is a DNA virus that has been infecting humans since ancient times, capable of causing a wide range of pathologies and affecting approximately 90% of the population. A 61-year-old male with no significant medical history presented with a 5-day history of imbalance and difficulty walking. Neurological examination revealed specific findings, including absent reflexes, bilateral asynergy, and gait abnormalities. Contrasting with Guillain-Barré Syndrome, lumbar puncture suggested a central nervous system infection. Serological testing confirmed Epstein-Barr virus (EBV) positivity, and intravenous immunoglobulin led to significant improvement. Electromyogram results suggested inflammatory/ipnfectious polyradiculopathy. Repeat EBV serology, showing strongly positive IgG and negative IgM, confirmed the diagnosis of Polyradiculoneuropathy secondary to EBV. This case underscores the rare neurological complications of EBV and the importance of considering viral infections in such presentations.
摘要：
爱泼斯坦-巴尔病毒(EBV)是一种自古以来就感染人类的DNA病毒,能够引起广泛的病理并影响大约90％的人口。一名61岁男性，无明显病史，有5天的失衡和行走困难史。神经系统检查揭示了具体的发现，包括缺乏反应，双边匿名，和步态异常。与格林-巴利综合征相比，腰椎穿刺提示中枢神经系统感染。血清学检测证实EB病毒（EBV）阳性，和静脉注射免疫球蛋白导致显著改善。肌电图结果提示炎性/感染性多神经根病。重复EBV血清学，显示强阳性IgG和阴性IgM，确诊为继发于EBV的多发性神经根神经病。此病例强调了EBV罕见的神经系统并发症以及在此类表现中考虑病毒感染的重要性。
