PDF(Pubmed)
Abstract：
Human infections caused by Pseudomonas citronellolis, an environmental bacterium, are infrequent, with only two cases related to uncommon urinary tract infections and bacteremia reported in recent years. All these cases typically occurred in elderly patients with compromised or decreased immune function. Simultaneously, the epithelial barrier disruption induced by invasive biopsy procedures or gastrointestinal disorders such as gastroenteritis provided a pathway for Pseudomonas citronellolis to infiltrate the organism. In this study, we present the first report of a case where Pseudomonas citronellolis and Escherichia coli were isolated from the inflamed appendix of a patient without underlying conditions. Compared to the Escherichia coli, Pseudomonas citronellolis has never been isolated in patients with appendicitis. We identified the species using MALDI-TOF MS and genetic sequencing. Based on our findings, we highlight the perspective that Pseudomonas citronellolis can colonize the intestines of healthy individuals and may trigger infections like appendicitis.
摘要：
由香型假单胞菌引起的人类感染，一种环境细菌，很少见，近年来仅报道了2例与罕见尿路感染和菌血症有关的病例。所有这些病例通常发生在免疫功能受损或降低的老年患者中。同时,由侵入性活检程序或胃肠道疾病如胃肠炎引起的上皮屏障破坏为香型假单胞菌渗透生物体提供了途径。在这项研究中,我们提供了一例病例的首例报告，其中从无潜在疾病的患者发炎的阑尾中分离出了香型假单胞菌和大肠杆菌。与大肠杆菌相比，在阑尾炎患者中从未分离出香茅假单胞菌。我们使用MALDI-TOFMS和基因测序鉴定了该物种。根据我们的发现,我们强调了香型假单胞菌可以在健康个体的肠道中定植,并可能引发阑尾炎等感染的观点.
