关键词: acquired immune deficiency syndrome aids antiretroviral therapy hiv hlh human immunodeficiency virus iris mycobacteria

来  源:   DOI:10.7759/cureus.53410   PDF(Pubmed)

Abstract:
Immune reconstitution inflammatory syndrome (IRIS) following initiation of antiretroviral therapy (ART) has variable incidence but is not uncommon and has the potential to cause long-term consequences and fatal outcomes in patients with HIV. Hemophagocytic lymphohistiocytosis (HLH) is a separate syndrome of excess immune activation, but may coexist with IRIS and necessitate a unique treatment approach. In this report, the case of a patient with newly diagnosed HIV/AIDS who was found to have both mycobacterial IRIS and HLH is presented.
摘要:
开始抗逆转录病毒治疗(ART)后的免疫重建炎症综合征(IRIS)的发病率不同,但并不少见,并且有可能在HIV患者中引起长期后果和致命后果。噬血细胞性淋巴组织细胞增生症(HLH)是一种过度免疫激活的单独综合征,但可能与IRIS共存,需要独特的治疗方法。在这份报告中,本文介绍了一例新诊断的HIV/AIDS患者,该患者同时患有分枝杆菌IRIS和HLH.
公众号