UNASSIGNED: We included patients with a SoS diagnosis and age < 18 years; all patients underwent a comprehensive neuropsychological assessment, including evaluation of cognition, adaptive functions through the Adaptive Behavior Assessment System-Second Edition (ABAS-II), and behavioral problems using the Achenbach Child Behavior Checklist (CBCL) and Conners\' Parent Rating Scale-Revised (CPRS-R:L) questionnaire. To investigate the presence of SD parents, the Sleep Disturbance Scale for Children (SDSC) was completed.
UNASSIGNED: Thirty-eight patients (M 61%, F 39%, mean age 11.1 ± 4.65 years) were included in the study. Although only two had a prior SD diagnosis, 71.1% (N = 27) exhibited pathological scores on SDSC. No statistically significant associations were found between positive SDSC results and genetic microdeletion, intellectual disability (ID), or other medical conditions/treatments. However, a positive correlation emerged between SDSC scores and Conners\' Global Index (p = 0.048) and Restless/Impulsive (p = 0.01) scores, CBCL externalizing (p = 0.02), internalizing (p = 0.01), and total scores (p = 0.05). Conversely, a negative linear relationship was observed between the SDSC score and the ABAS GAC and ABAS CAD scores (p = 0.025).
UNASSIGNED: We detected an SD in 71.1% of our sample, with a positive relation between SD and internalizing and externalizing symptom levels, especially hyperactivity and impulsivity. Our study demonstrated a high prevalence of SD in pediatric patients with SoS, highlighting that all patients should be screened for this problem, which has a great impact on the quality of life of patients and their families.
■我们纳入了SoS诊断且年龄<18岁的患者;所有患者都接受了全面的神经心理学评估,包括认知评估,通过自适应行为评估系统-第二版(ABAS-II)实现自适应功能,和行为问题使用Achenbach儿童行为清单(CBCL)和Conners父母评定量表修订(CPRS-R:L)问卷。为了调查SD父母的存在,儿童睡眠障碍量表(SDSC)完成。
■38名患者(M61%,F39%,平均年龄11.1±4.65岁)纳入研究。虽然只有两个人先前有SD诊断,71.1%(N=27)的SDSC表现出病理评分。SDSC阳性结果与遗传微缺失之间无统计学意义的关联,智力残疾(ID),或其他医疗条件/治疗。然而,SDSC得分与康纳斯全球指数(p=0.048)和不安/冲动(p=0.01)得分之间出现正相关,CBCL外部化(p=0.02),内化(p=0.01),和总分(p=0.05)。相反,SDSC评分与ABASGAC和ABASCAD评分呈负线性关系(p=0.025).
■我们在71.1%的样本中检测到SD,SD与内化和外化症状水平之间存在正相关关系,尤其是多动和冲动。我们的研究表明,儿童SoS患者的SD患病率很高,强调所有患者都应该接受这个问题的筛查,对患者及其家属的生活质量有很大影响。